4XSS

Insulin-like growth factor I in complex with site 1 of a hybrid insulin receptor / Type 1 insulin-like growth factor receptor

Summary for 4XSS

Entry DOI	10.2210/pdb4xss/pdb
Related	3W11 3W12 3W13 3W14 4OGA 4XST
Descriptor	Insulin-like growth factor I, Insulin receptor, Insulin-like growth factor receptor alpha-CT peptide, ... (7 entities in total)
Functional Keywords	cell surface receptor/immune system, insulin receptor, ct peptide, insulin-like growth factor receptor, hormone receptor-hormone-immune system complex, hormone-hormone receptor complex, hormone/hormone receptor
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	48126.83
Authors	Lawrence, C.,Kong, G.K.-W.,Menting, J.G.,Lawrence, M.C. (deposition date: 2015-01-22, release date: 2015-06-10, Last modification date: 2023-09-27)
Primary citation	Menting, J.G.,Lawrence, C.F.,Kong, G.K.,Margetts, M.B.,Ward, C.W.,Lawrence, M.C. Structural Congruency of Ligand Binding to the Insulin and Insulin/Type 1 Insulin-like Growth Factor Hybrid Receptors. Structure, 23:1271-1282, 2015 Cited by PubMed: 26027733 DOI: 10.1016/j.str.2015.04.016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation