4XST

Structure of the endoglycosidase-H treated L1-CR domains of the human insulin receptor in complex with residues 697-719 of the human insulin receptor (A-isoform)

Summary for 4XST

Entry DOI	10.2210/pdb4xst/pdb
Descriptor	Insulin receptor, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	insulin receptor, insulin micro-receptor, hormone-hormone receptor complex, hormone/hormone receptor
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	40246.99
Authors	Menting, J.G.,Lawrence, C.F.,Kong, G.K.-W.,Lawrence, M.C. (deposition date: 2015-01-22, release date: 2015-06-10, Last modification date: 2023-09-27)
Primary citation	Menting, J.G.,Lawrence, C.F.,Kong, G.K.,Margetts, M.B.,Ward, C.W.,Lawrence, M.C. Structural Congruency of Ligand Binding to the Insulin and Insulin/Type 1 Insulin-like Growth Factor Hybrid Receptors. Structure, 23:1271-1282, 2015 Cited by PubMed: 26027733 DOI: 10.1016/j.str.2015.04.016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation