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4XST

Structure of the endoglycosidase-H treated L1-CR domains of the human insulin receptor in complex with residues 697-719 of the human insulin receptor (A-isoform)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(E)
Insulin receptorpolymer31736231.81UniProt (P06213)
Pfam (PF01030)
Pfam (PF00757)
Homo sapiens (Human)IR
2B
(F)
Insulin receptorpolymer232792.11UniProt (P15127)Rattus norvegicusIR
3C
(A)
alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched367.31In PDB
GlyTouCan (G86851RC)
4D, E, F
(E)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.23Chemie (NAG)
5G, H
(E)
SULFATE IONnon-polymer96.12Chemie (SO4)
Sequence modifications
E: 1 - 310 (UniProt: P06213)
PDBExternal DatabaseDetails
His 144Tyr 171conflict
Ser 311-expression tag
Ser 312-expression tag
Ser 313-expression tag
Leu 314-expression tag
Val 315-expression tag
Pro 316-expression tag
Arg 317-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight39023.9
BranchedNumber of molecules1
Total formula weight367.3
Non-Polymers*Number of molecules5
Total formula weight855.8
All*Total formula weight40247.0
*Water molecules are not included.

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PDB entries from 2025-07-30

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