4XSS

Insulin-like growth factor I in complex with site 1 of a hybrid insulin receptor / Type 1 insulin-like growth factor receptor

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0005179	molecular_function	hormone activity
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0008083	molecular_function	growth factor activity

Functional Information from PROSITE/UniProt

site_id	PS00262
Number of Residues	15
Details	INSULIN Insulin family signature. CCFRsCDlrrLemyC

Chain	Residue	Details
B	CYS47-CYS61

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	SITE: Insulin-binding => ECO:0000305

Chain	Residue	Details
E	PHE39

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site_id	SWS_FT_FI2
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16894147, ECO:0000269|PubMed:23302862, ECO:0000269|PubMed:2983222

Chain	Residue	Details
E	ASN16

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site_id	SWS_FT_FI3
Number of Residues	3
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16894147, ECO:0000269|PubMed:23302862

Chain	Residue	Details
E	ASN25
E	ASN111
E	ASN255

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site_id	SWS_FT_FI4
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
E	ASN78
E	ASN295

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site_id	SWS_FT_FI5
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16894147, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:23302862

Chain	Residue	Details
E	ASN215

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues
Details	M-CSA 246

Chain

Residue

Details

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