4XSS
Insulin-like growth factor I in complex with site 1 of a hybrid insulin receptor / Type 1 insulin-like growth factor receptor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B | Insulin-like growth factor I | polymer | 70 | 7663.8 | 1 | UniProt (P05019) Pfam (PF00049) In PDB | Homo sapiens (Human) | IGF-I,Mechano growth factor,MGF,Somatomedin-C |
2 | E | Insulin receptor | polymer | 317 | 36231.8 | 1 | UniProt (P06213) Pfam (PF01030) Pfam (PF00757) In PDB | Homo sapiens (Human) | IR |
3 | F | Insulin-like growth factor receptor alpha-CT peptide | polymer | 16 | 1947.2 | 1 | UniProt (by SIFTS) (P08069) In PDB | Homo sapiens | |
4 | A | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) | |||
5 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
6 | E | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
7 | E | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) |
Sequence modifications
E: 1 - 310 (UniProt: P06213)
PDB | External Database | Details |
---|---|---|
His 144 | Tyr 171 | conflict |
Ser 311 | - | expression tag |
Ser 312 | - | expression tag |
Ser 313 | - | expression tag |
Leu 314 | - | expression tag |
Val 315 | - | expression tag |
Pro 316 | - | expression tag |
Arg 317 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 45842.7 | |
Branched | Number of molecules | 2 |
Total formula weight | 1303.2 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 980.9 | |
All* | Total formula weight | 48126.8 |