4I04
Structure of zymogen of cathepsin B1 from Schistosoma mansoni
Summary for 4I04
Entry DOI | 10.2210/pdb4i04/pdb |
Related | 3QSD 3S3Q 3S3R 4I05 4I07 |
Descriptor | Cathepsin B-like peptidase (C01 family), 1,2-ETHANEDIOL (3 entities in total) |
Functional Keywords | peptidase, digestive tract, hydrolase |
Biological source | Schistosoma mansoni (Blood fluke) |
Total number of polymer chains | 4 |
Total formula weight | 147285.24 |
Authors | Rezacova, P.,Jilkova, A.,Brynda, J.,Horn, M.,Mares, M. (deposition date: 2012-11-16, release date: 2014-02-05, Last modification date: 2023-11-08) |
Primary citation | Jilkova, A.,Horn, M.,Rezacova, P.,Maresova, L.,Fajtova, P.,Brynda, J.,Vondrasek, J.,McKerrow, J.H.,Caffrey, C.R.,Mares, M. Activation route of the Schistosoma mansoni cathepsin B1 drug target: structural map with a glycosaminoglycan switch Structure, 22:1786-1798, 2014 Cited by PubMed: 25456815DOI: 10.1016/j.str.2014.09.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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