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4I04

Structure of zymogen of cathepsin B1 from Schistosoma mansoni

Summary for 4I04
Entry DOI10.2210/pdb4i04/pdb
Related3QSD 3S3Q 3S3R 4I05 4I07
DescriptorCathepsin B-like peptidase (C01 family), 1,2-ETHANEDIOL (3 entities in total)
Functional Keywordspeptidase, digestive tract, hydrolase
Biological sourceSchistosoma mansoni (Blood fluke)
Total number of polymer chains4
Total formula weight147285.24
Authors
Rezacova, P.,Jilkova, A.,Brynda, J.,Horn, M.,Mares, M. (deposition date: 2012-11-16, release date: 2014-02-05, Last modification date: 2023-11-08)
Primary citationJilkova, A.,Horn, M.,Rezacova, P.,Maresova, L.,Fajtova, P.,Brynda, J.,Vondrasek, J.,McKerrow, J.H.,Caffrey, C.R.,Mares, M.
Activation route of the Schistosoma mansoni cathepsin B1 drug target: structural map with a glycosaminoglycan switch
Structure, 22:1786-1798, 2014
Cited by
PubMed: 25456815
DOI: 10.1016/j.str.2014.09.015
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.95 Å)
Structure validation

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