4I04
Structure of zymogen of cathepsin B1 from Schistosoma mansoni
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Cathepsin B-like peptidase (C01 family) | polymer | 323 | 36728.2 | 4 | UniProt (Q8MNY2) Pfam (PF08127) Pfam (PF00112) | Schistosoma mansoni (Blood fluke) | Cathepsin B1 isotype 1 |
| 2 | E, F, G, H, I... (A, B, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 3 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 519 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 323 (UniProt: Q8MNY2)
| PDB | External Database | Details |
|---|---|---|
| Ser 100 | Cys 117 | engineered mutation |
| Ala 168 | Thr 185 | engineered mutation |
| Ala 283 | Thr 300 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 146912.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 372.4 | |
| All* | Total formula weight | 147285.2 |
