4I04
Structure of zymogen of cathepsin B1 from Schistosoma mansoni
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Cathepsin B-like peptidase (C01 family) | polymer | 323 | 36728.2 | 4 | UniProt (Q8MNY2) Pfam (PF08127) Pfam (PF00112) In PDB | Schistosoma mansoni (Blood fluke) | Cathepsin B1 isotype 1 |
2 | A, B, D | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
3 | water | water | 18.0 | 519 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 323 (UniProt: Q8MNY2)
PDB | External Database | Details |
---|---|---|
Ser 100 | Cys 117 | engineered mutation |
Ala 168 | Thr 185 | engineered mutation |
Ala 283 | Thr 300 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 146912.8 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 372.4 | |
All* | Total formula weight | 147285.2 |