3QSD
Structure of cathepsin B1 from Schistosoma mansoni in complex with CA074 inhibitor
Summary for 3QSD
| Entry DOI | 10.2210/pdb3qsd/pdb |
| Related PRD ID | PRD_001032 |
| Descriptor | Cathepsin B-like peptidase (C01 family), [PROPYLAMINO-3-HYDROXY-BUTAN-1,4-DIONYL]-ISOLEUCYL-PROLINE, DI(HYDROXYETHYL)ETHER, ... (5 entities in total) |
| Functional Keywords | cysteine peptidase, digestive tract, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Schistosoma mansoni (Blood fluke) |
| Total number of polymer chains | 1 |
| Total formula weight | 29116.92 |
| Authors | Rezacova, P.,Jilkova, A.,Brynda, J.,Horn, M.,Mares, M. (deposition date: 2011-02-21, release date: 2011-08-10, Last modification date: 2023-09-13) |
| Primary citation | Jilkova, A.,Rezacova, P.,Lepsik, M.,Horn, M.,Vachova, J.,Fanfrlik, J.,Brynda, J.,McKerrow, J.H.,Caffrey, C.R.,Mares, M. Structural Basis for Inhibition of Cathepsin B Drug Target from the Human Blood Fluke, Schistosoma mansoni. J.Biol.Chem., 286:35770-35781, 2011 Cited by PubMed: 21832058DOI: 10.1074/jbc.M111.271304 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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