4I05

Structure of intermediate processing form of cathepsin B1 from Schistosoma mansoni

Summary for 4I05

Entry DOI	10.2210/pdb4i05/pdb
Related	3QSD 3S3Q 3S3R 4I04 4I07
Descriptor	Cathepsin B-like peptidase (C01 family), SODIUM ION (3 entities in total)
Functional Keywords	peptidase, digestive tract, hydrolase
Biological source	Schistosoma mansoni (Blood fluke)
Total number of polymer chains	1
Total formula weight	32326.40
Authors	Rezacova, P.,Jilkova, A.,Brynda, J.,Horn, M.,Mares, M. (deposition date: 2012-11-16, release date: 2014-02-05, Last modification date: 2023-12-06)
Primary citation	Jilkova, A.,Horn, M.,Rezacova, P.,Maresova, L.,Fajtova, P.,Brynda, J.,Vondrasek, J.,McKerrow, J.H.,Caffrey, C.R.,Mares, M. Activation route of the Schistosoma mansoni cathepsin B1 drug target: structural map with a glycosaminoglycan switch Structure, 22:1786-1798, 2014 Cited by PubMed: 25456815 DOI: 10.1016/j.str.2014.09.015 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation