4DJ9
Human vinculin head domain Vh1 (residues 1-258) in complex with the talin vinculin binding site 50 (VBS50, residues 2078-2099)
Summary for 4DJ9
Entry DOI | 10.2210/pdb4dj9/pdb |
Related | 1rkc 1rke 1syq 3s90 3tj5 3tj6 |
Descriptor | Vinculin, Talin-1 (3 entities in total) |
Functional Keywords | cytoskeleton, focal adhesion, protein-protein interaction, four-helix bundle, cell adhesion, f-actin, cytosol |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cytoskeleton: P18206 Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side (By similarity): Q9Y490 |
Total number of polymer chains | 2 |
Total formula weight | 31807.72 |
Authors | Yogesha, S.D.,Rangarajan, E.S.,Vonrhein, C.,Bricogne, G.,Izard, T. (deposition date: 2012-02-01, release date: 2012-02-29, Last modification date: 2024-02-28) |
Primary citation | Yogesha, S.D.,Rangarajan, E.S.,Vonrhein, C.,Bricogne, G.,Izard, T. Crystal structure of vinculin in complex with vinculin binding site 50 (VBS50), the integrin binding site 2 (IBS2) of talin. Protein Sci., 21:583-588, 2012 Cited by PubMed: 22334306DOI: 10.1002/pro.2041 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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