4XSS
Insulin-like growth factor I in complex with site 1 of a hybrid insulin receptor / Type 1 insulin-like growth factor receptor
Summary for 4XSS
Entry DOI | 10.2210/pdb4xss/pdb |
Related | 3W11 3W12 3W13 3W14 4OGA 4XST |
Descriptor | Insulin-like growth factor I, Insulin receptor, Insulin-like growth factor receptor alpha-CT peptide, ... (7 entities in total) |
Functional Keywords | cell surface receptor/immune system, insulin receptor, ct peptide, insulin-like growth factor receptor, hormone receptor-hormone-immune system complex, hormone-hormone receptor complex, hormone/hormone receptor |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 48126.83 |
Authors | Lawrence, C.,Kong, G.K.-W.,Menting, J.G.,Lawrence, M.C. (deposition date: 2015-01-22, release date: 2015-06-10, Last modification date: 2023-09-27) |
Primary citation | Menting, J.G.,Lawrence, C.F.,Kong, G.K.,Margetts, M.B.,Ward, C.W.,Lawrence, M.C. Structural Congruency of Ligand Binding to the Insulin and Insulin/Type 1 Insulin-like Growth Factor Hybrid Receptors. Structure, 23:1271-1282, 2015 Cited by PubMed: 26027733DOI: 10.1016/j.str.2015.04.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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