2XW9
Crystal Structure of Complement Factor D mutant S183A
Summary for 2XW9
| Entry DOI | 10.2210/pdb2xw9/pdb |
| Related | 1BIO 1DFP 1DIC 1DST 1DSU 1FDP 1HFD 2XWA 2XWB 2XWJ |
| Descriptor | COMPLEMENT FACTOR D, GLYCEROL (3 entities in total) |
| Functional Keywords | immune system, hydrolase, serine protease, alternative pathway |
| Biological source | HOMO SAPIENS (HUMAN) |
| Cellular location | Secreted: P00746 |
| Total number of polymer chains | 1 |
| Total formula weight | 24791.18 |
| Authors | Forneris, F.,Ricklin, D.,Wu, J.,Tzekou, A.,Wallace, R.S.,Lambris, J.D.,Gros, P. (deposition date: 2010-11-01, release date: 2011-01-12, Last modification date: 2023-12-20) |
| Primary citation | Forneris, F.,Ricklin, D.,Wu, J.,Tzekou, A.,Wallace, R.S.,Lambris, J.D.,Gros, P. Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation. Science, 330:1816-, 2010 Cited by PubMed: 21205667DOI: 10.1126/SCIENCE.1195821 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.2 Å) |
Structure validation
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