1FDP
PROENZYME OF HUMAN COMPLEMENT FACTOR D, RECOMBINANT PROFACTOR D
Summary for 1FDP
Entry DOI | 10.2210/pdb1fdp/pdb |
Descriptor | PROENZYME OF COMPLEMENT FACTOR D (2 entities in total) |
Functional Keywords | serine protease, complement, factor d, profactor d, zymogen, proenzyme, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P00746 |
Total number of polymer chains | 4 |
Total formula weight | 100586.53 |
Authors | Jing, H.,Macon, K.J.,Moore, D.,Delucas, L.J.,Volanakis, J.E.,Narayana, S.V.L. (deposition date: 1998-12-03, release date: 1999-12-03, Last modification date: 2023-08-09) |
Primary citation | Jing, H.,Macon, K.J.,Moore, D.,DeLucas, L.J.,Volanakis, J.E.,Narayana, S.V. Structural basis of profactor D activation: from a highly flexible zymogen to a novel self-inhibited serine protease, complement factor D. Embo J., 18:804-814, 1999 Cited by PubMed: 10022823DOI: 10.1093/emboj/18.4.804 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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