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2XW9

Crystal Structure of Complement Factor D mutant S183A

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
COMPLEMENT FACTOR Dpolymer22824422.81UniProt (P00746)
Pfam (PF00089)
HOMO SAPIENS (HUMAN)ADIPSIN, C3 CONVERTASE ACTIVATOR, PROPERDIN FACTOR D
2B, C, D, E
(A)
GLYCEROLnon-polymer92.14Chemie (GOL)
3F
(A)
waterwater18.0301Chemie (HOH)
Sequence modifications
A: 1 - 228 (UniProt: P00746)
PDBExternal DatabaseDetails
Ala 183Ser 208engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight24422.8
Non-Polymers*Number of molecules4
Total formula weight368.4
All*Total formula weight24791.2
*Water molecules are not included.

239149

PDB entries from 2025-07-23

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