1DST

MUTANT OF FACTOR D WITH ENHANCED CATALYTIC ACTIVITY

Summary for 1DST

DescriptorFACTOR D (2 entities in total)
Functional Keywordscomplement activating enzyme, hydrolase, serine protease, factor d, hydrolase (serine protease)
Biological sourceHomo sapiens (human)
Cellular locationSecreted P00746
Total number of polymer chains1
Total molecular weight24600.01
Authors
Narayana, S.V.L.,Volanakis, J.E. (deposition date: 1995-09-13, release date: 1996-07-11, Last modification date: 2011-07-13)
Primary citation
Kim, S.,Narayana, S.V.,Volanakis, J.E.
Crystal structure of a complement factor D mutant expressing enhanced catalytic activity.
J.Biol.Chem., 270:24399-24405, 1995
PubMed: 7592653 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.270.41.24399
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers18 1.3% 6.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-09-23