2XEW

Crystal structure of K11-linked diubiquitin

Summary for 2XEW

Related1XQQ 2JF5 1UBQ 2GBJ 2G45 2GBK 1ZGU 2J7Q 2WDT 1F9J 2BGF 1FXT 1TBE 2AYO 1GJZ 1XD3 1NBF 1G6J 1UBI 1SIF 1D3Z 2W9N 1OGW 2GBN 2GBM 1YX5 1C3T 1Q5W 1S1Q 1YX6
DescriptorUBIQUITIN, 1,2-ETHANEDIOL, CHLORIDE ION, ... (5 entities in total)
Functional Keywordsprotein degradation, proteasome, cell cycle, deubiquitination
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains12
Total molecular weight104603.5
Authors
Bremm, A.,Freund, S.M.V.,Komander, D. (deposition date: 2010-05-18, release date: 2010-07-14, Last modification date: 2019-07-31)
Primary citation
Bremm, A.,Freund, S.M.V.,Komander, D.
Lys11-Linked Ubiquitin Chains Adopt Compact Conformations and are Preferentially Hydrolyzed by the Deubiquitinase Cezanne
Nat.Struct.Mol.Biol., 17:939-, 2010
PubMed: 20622874 (PDB entries with the same primary citation)
DOI: 10.1038/NSMB.1873
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.249200 5.9% 0.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report