2WDT

Crystal structure of Plasmodium falciparum UCHL3 in complex with the suicide inhibitor UbVME

Summary for 2WDT

Related1XQQ 2JF5 2GBJ 1UBQ 1ZGU 2G45 2GBK 2J7Q 1F9J 2BGF 1FXT 1TBE 2AYO 1XD3 1GJZ 1UBI 1G6J 1NBF 1SIF 1D3Z 2W9N 1OGW 2GBN 2GBM 1YX5 1C3T 1Q5W 1S1Q 1YX6
DescriptorUBIQUITIN CARBOXYL-TERMINAL HYDROLASE L3, UBIQUITIN, CHLORIDE ION, ... (4 entities in total)
Functional Keywordshydrolase-protein binding complex, enzyme-ligand complex, ubiquitin isopeptidase, uch-l superfamily, cystein proteinase, peptidase_c12, hydrolase, hydrolase/protein binding
Biological sourcePLASMODIUM FALCIPARUM (MALARIA PARASITE)
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Total number of polymer chains4
Total molecular weight71169.37
Authors
Weihofen, W.A.,Artavanis-Tsakonas, K.,Gaudet, R.,Ploegh, H.L. (deposition date: 2009-03-26, release date: 2009-12-29, Last modification date: 2011-07-13)
Primary citation
Artavanis-Tsakonas, K.,Weihofen, W.A.,Antos, J.M.,Coleman, B.I.,Comeaux, C.A.,Duraisingh, M.T.,Gaudet, R.,Ploegh, H.L.
Characterization and Structural Studies of the Plasmodium Falciparum Ubiquitin and Nedd8 Hydrolase Uchl3.
J.Biol.Chem., 285:6857-, 2010
PubMed: 20042598 (PDB entries with the same primary citation)
DOI: 10.1074/JBC.M109.072405
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.3 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.237506.6%6.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report