2WMB

Structural and thermodynamic consequences of cyclization of peptide ligands for the recruitment site of cyclin A

Summary for 2WMB

Related1H08 1PYE 2VTH 2B53 1V1K 1H25 1KE7 1OKV 1PXK 2WIH 2BHH 2VTA 2UUE 1GZ8 1E1V 1OL2 1H27 1JSV 2WHA 2B52 1KE5 1FIN 2C5O 2C68 2VTT 1P2A 2VTQ 2C4G 1W0X 1H1Q 2W05 1PXO 1KE9 1HCK 2A0C 1JSU 1PXN 2UZE 2VTM 2V0D 1OIQ 1H1R 2IW8 1HCL 1PW2 1GIH 2WHB 2VTN 2W06 1JST 1OIU 1B38 1PXM 1FQ1 1VYW 1H1P 2WMA 2C69 1URC 1PXI 2C6I 1YKR 2W17 2C5Y 2UZD 2C6K 1WCC 2J9M 1VYZ 2VTI 1JVP 1W98 2WIP 1PKD 1P5E 2VTS 2C5P 2UZN 2B54 1PXJ 1KE6 2UZL 2CCI 2BKZ 2G9X 1Y91 2IW6 1GIJ 1R78 1H0V 2IW9 1W8C 1BUH 2BPM 2BTS 1FVV 1OKW 2VTP 2A4L 2C6T 1FVT 1QMZ 2W1H 2VU3 1OGU 2B55 1PF8 1H1S 2C5V 2JGZ 2BHE 1URW 1OIY 2C6L 2C6O 1F5Q 2VTL 1OL1 1H01 2UZB 2WFY 1OIR 1OI9 2VTJ 2CJM 2WEV 2C5X 2C5N 2C6M 1OIT 1GY3 2V22 1DI8 1GII 2VV9 1E9H 2VTO 1DM2 1H24 2UZO 2EXM 1H00 2CLX 1PXP 2CCH 1B39 2BTR 1AQ1 1H0W 1G5S 1CKP 1KE8 1PXL 1H28 2VTR 1H26 1E1X 1H07 1Y8Y
DescriptorCELL DIVISION PROTEIN KINASE 2, CYCLIN-A2, LINEAR RKLFD, ... (5 entities in total)
Functional Keywordscell cycle, cell division, anti-oncogene, serine/threonine-protein kinase, phosphorylation, nucleotide-binding, transcription regulation, chromatin regulator, recruitment, transcription, nucleus, mitosis, atp-binding, transferase
Biological sourceHOMO SAPIENS
Cellular locationNucleus P20248
Total number of polymer chains5
Total molecular weight129146.78
Authors
Robertson, G.F.,Endicott, J.A.,Noble, M.E.M.,McDonnell, J.M. (deposition date: 2009-06-30, release date: 2010-09-01, Last modification date: 2011-07-13)
Primary citation
Robertson, G.F.,Endicott, J.A.,Noble, M.E.M.,Mcdonnell, J.M.
Structural and Thermodynamic Consequences of Cyclization of Peptide Ligands for the Recruitment Site of Cyclin A
To be Published,
Experimental method
X-RAY DIFFRACTION (2.6 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.284111.2%4.9%5.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report