1H25
CDK2/Cyclin A in complex with an 11-residue recruitment peptide from retinoblastoma-associated protein
Summary for 1H25
Entry DOI | 10.2210/pdb1h25/pdb |
Related | 1AD6 1AQ1 1B38 1B39 1BUH 1CKP 1DI8 1DM2 1E1V 1E1X 1E9H 1F5Q 1FIN 1FQ1 1FVT 1FVV 1G5S 1GH6 1GIH 1GII 1GIJ 1GUX 1GY3 1GZ8 1QMZ |
Descriptor | CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, RETINOBLASTOMA-ASSOCIATED PROTEIN, ... (4 entities in total) |
Functional Keywords | transferase, cell cycle, protein kinase, cyclin, cdk2, recruitment, peptide specificity |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Nucleus: P20248 P06400 |
Total number of polymer chains | 5 |
Total formula weight | 129785.34 |
Authors | Tews, I.,Cheng, K.Y.,Lowe, E.D.,Noble, M.E.M.,Brown, N.R.,Gul, S.,Gamblin, S.,Johnson, L.N. (deposition date: 2002-07-31, release date: 2003-02-01, Last modification date: 2024-10-16) |
Primary citation | Lowe, E.D.,Tews, I.,Cheng, K.Y.,Brown, N.R.,Gul, S.,Noble, M.E.M.,Gamblin, S.,Johnson, L.N. Specificity Determinants of Recruitment Peptides Bound to Phospho-Cdk2/Cyclin A Biochemistry, 41:15625-, 2002 Cited by PubMed: 12501191DOI: 10.1021/BI0268910 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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