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2A4L

Human cyclin-dependent kinase 2 in complex with roscovitine

Summary for 2A4L
Entry DOI10.2210/pdb2a4l/pdb
Related1HCK
DescriptorHomo sapiens cyclin-dependent kinase 2, R-ROSCOVITINE (3 entities in total)
Functional Keywordstransferase, serine/threonine protein kinase, atp-binding, cell cycle, cell division, roscovitine, phosphorylation
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight34330.94
Authors
De Azevedo Jr., W.F.,Kim, S.H. (deposition date: 2005-06-29, release date: 2006-10-03, Last modification date: 2024-02-14)
Primary citationDe Azevedo, W.F.,Leclerc, S.,Meijer, L.,Havlicek, L.,Strnad, M.,Kim, S.H.
Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine.
Eur.J.Biochem., 243:518-526, 1997
Cited by
PubMed: 9030780
DOI: 10.1111/j.1432-1033.1997.0518a.x
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

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