2VWF

Grb2 SH3C (2)

Summary for 2VWF

• Entry DOI: 10.2210/pdb2vwf/pdb
• Related: 1AZE 1BM2 1BMB 1CJ1 1FHS 1FYR 1GCQ 1GFC 1GFD 1GHU 1GRI 1IO6 1JYQ 1JYR 1JYU 1QG1 1TZE 1X0N 1ZFP 2AOA 2AOB 2H46 2VVK
• Descriptor: GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, GRB2-ASSOCIATED-BINDING PROTEIN 2 (3 entities in total)
• Functional Keywords: polymorphism, phosphoprotein, golgi apparatus, grb2, alternative splicing, host-virus interaction, sh3c, signaling, sh2 domain, sh3 domain, protein-binding, protein binding
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Golgi apparatus (By similarity): P62993; Cytoplasm: Q9UQC2
• Total number of polymer chains: 2
• Total formula weight: 8388.32

Authors

Harkiolaki, M.,Tsirka, T.,Feller, S.M. (deposition date: 2008-06-24, release date: 2009-05-19, Last modification date: 2023-12-13)

• Primary citation: Harkiolaki, M.,Tsirka, T.,Lewitzky, M.,Simister, P.C.,Joshi, D.,Bird, L.E.,Jones, E.Y.,O'Reilly, N.,Feller, S.M.; Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.; Structure, 17:809-, 2009; PubMed: 19523899; DOI: 10.1016/J.STR.2009.03.017

Experimental method

X-RAY DIFFRACTION (1.58 Å)