1JYQ
Xray Structure of Grb2 SH2 Domain Complexed with a Highly Affine Phospho Peptide
Summary for 1JYQ
Entry DOI | 10.2210/pdb1jyq/pdb |
Related | 1JYR 1JYU |
Related PRD ID | PRD_000409 |
Descriptor | GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, mAZ-pY-(alpha Me)pY-N-NH2 peptide inhibitor (3 entities in total) |
Functional Keywords | receptor binding, regulatory, signaling protein-signaling protein inhibitor, signaling protein-peptide inhibitor complex, signaling protein/peptide inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 23706.32 |
Authors | Nioche, P.,Liu, W.-Q.,Broutin, I.,Charbonnier, F.,Latreille, M.-T.,Vidal, M.,Roques, B.,Garbay, C.,Ducruix, A. (deposition date: 2001-09-13, release date: 2002-03-13, Last modification date: 2024-07-10) |
Primary citation | Nioche, P.,Liu, W.Q.,Broutin, I.,Charbonnier, F.,Latreille, M.T.,Vidal, M.,Roques, B.,Garbay, C.,Ducruix, A. Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor. J.Mol.Biol., 315:1167-1177, 2002 Cited by PubMed: 11827484DOI: 10.1006/jmbi.2001.5299 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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