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1JYQ

Xray Structure of Grb2 SH2 Domain Complexed with a Highly Affine Phospho Peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BGROWTH FACTOR RECEPTOR-BOUND PROTEIN 2polymer9611071.62UniProt (P29354)
Pfam (PF00017)
UniProt (by SIFTS) (P62993)
In PDB
Homo sapiens (human)GRB2 ADAPTER PROTEIN
2L, HmAZ-pY-(alpha Me)pY-N-NH2 peptide inhibitorpolymer4765.62BIRD (PRD_000409)
3waterwater18.0166Chemie (HOH)
Sequence modifications
A, B: 60 - 151 (UniProt: P29354)
PDBExternal DatabaseDetails
Gly 56-CLONING ARTIFACT
Ser 57-CLONING ARTIFACT
Met 58-CLONING ARTIFACT
Ala 59-CLONING ARTIFACT
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight23674.3
All*Total formula weight23674.3
*Water molecules are not included.

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PDB entries from 2024-04-24

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