1JYQ
Xray Structure of Grb2 SH2 Domain Complexed with a Highly Affine Phospho Peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 | polymer | 96 | 11071.6 | 2 | UniProt (P29354) Pfam (PF00017) UniProt (by SIFTS) (P62993) | Homo sapiens (human) | GRB2 ADAPTER PROTEIN |
| 2 | C, D (L, H) | mAZ-pY-(alpha Me)pY-N-NH2 peptide inhibitor | polymer | 4 | 781.6 | 2 | BIRD (PRD_000409) | ||
| 3 | E, F, G, H (A, B, L, H) | water | water | 18.0 | 166 | Chemie (HOH) |
Sequence modifications
A, B: 60 - 151 (UniProt: P29354)
| PDB | External Database | Details |
|---|---|---|
| Gly 56 | - | cloning artifact |
| Ser 57 | - | cloning artifact |
| Met 58 | - | cloning artifact |
| Ala 59 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 23706.3 | |
| All* | Total formula weight | 23706.3 |
