2VWF

Grb2 SH3C (2)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2	polymer	58	6612.2	1	UniProt (P62993) Pfam (PF00018)	HOMO SAPIENS (HUMAN)	ADAPTER PROTEIN GRB2, SH2/SH3 ADAPTER GRB2, PROTEIN ASH, GRB2 SH3C
2	B (B)	GRB2-ASSOCIATED-BINDING PROTEIN 2	polymer	15	1776.1	1	UniProt (Q9UQC2)	HOMO SAPIENS	GROWTH FACTOR RECEPTOR BOUND PROTEIN 2-ASSOCIATED PROTEIN 2, GRB2-ASSOCIATED BINDER 2, PP100, GAB2
3	C, D (A, B)	water	water		18.0	42	Chemie (HOH)

Sequence modifications

A: -1 - 0 (PDB: 2VWF)
A: 1 - 56 (UniProt: P62993)

PDB	External Database	Details
Ala 54	Pro 212	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	8388.3
All*	Total formula weight	8388.3

*Water molecules are not included.