2J0Z
p53 tetramerization domain wild type
Summary for 2J0Z
Entry DOI | 10.2210/pdb2j0z/pdb |
Related | 1A1U 1AIE 1C26 1DT7 1GZH 1H26 1HS5 1JSP 1KZY 1MA3 1OLG 1OLH 1PES 1PET 1SAE 1SAF 1SAG 1SAH 1SAI 1SAJ 1SAK 1SAL 1TSR 1TUP 1UOL 1XQH 1YCQ 1YCR 1YCS 2AC0 2ADY 2AHI 2ATA 2B3G 2BIM 2BIN 2BIO 2BIP 2BIQ 2F1X 2FEJ 2J10 2J11 2TOH 3SAK |
NMR Information | BMRB: 7251 |
Descriptor | CELLULAR TUMOR ANTIGEN P53 (1 entity in total) |
Functional Keywords | p53, zinc, activator, apoptosis, wild type, cell cycle, acetylation, dna-binding, polymorphism, tetramerization domain, transcription regulation, anti-oncogene, nuclear protein, phosphorylation, li-fraumeni syndrome, host-virus interaction, disease mutation, alternative splicing, glycoprotein, transcription, metal-binding |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: P04637 |
Total number of polymer chains | 4 |
Total formula weight | 15064.88 |
Authors | Carbajo, R.J.,Mora, P.,Sanchez del Pino, M.M.,Perez-Paya, E.,Pineda-Lucena, A. (deposition date: 2006-08-08, release date: 2007-08-28, Last modification date: 2024-05-15) |
Primary citation | Mora, P.,Carbajo, R.J.,Pineda-Lucena, A.,Sanchez del Pino, M.M.,Perez-Paya, E. Solvent-exposed residues located in the beta-sheet modulate the stability of the tetramerization domain of p53--a structural and combinatorial approach. Proteins, 71:1670-1685, 2008 Cited by PubMed: 18076077DOI: 10.1002/prot.21854 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
Download full validation report