1P17

Hypoxanthine Phosphoribosyltransferase from Trypanosoma cruzi, K68R mutant, complexed with the product IMP

1P17 の概要

• エントリーDOI: 10.2210/pdb1p17/pdb
• 関連するPDBエントリー: 1p18 1p19 1tc1 1tc2
• 分子名称: hypoxanthine phosphoribosyltransferase, INOSINIC ACID (3 entities in total)
• 機能のキーワード: transferase, glycosyltransferase, phosphoribosyltransferase, nucleotide metabolism, purine salvage, product complex
• 由来する生物種: Trypanosoma cruzi
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 103886.50

構造登録者

Medrano, F.J.,Eakin, A.E.,Craig III, S.P. (登録日: 2003-04-11, 公開日: 2004-05-18, 最終更新日: 2024-02-14)

• 主引用文献: Canyuk, B.,Medrano, F.J.,Wenck, M.A.,Focia, P.J.,Eakin, A.E.,Craig III, S.P.; Interactions at the dimer interface influence the relative efficiencies for purine nucleotide synthesis and pyrophosphorolysis in a phosphoribosyltransferase.; J.Mol.Biol., 335:905-921, 2004; PubMed: 14698288; DOI: 10.1016/j.jmb.2003.11.012

実験手法

X-RAY DIFFRACTION (2.7 Å)