1P19
Hypoxanthine Phosphoribosyltransferase from Trypanosoma cruzi, in complex with the product IMP
Summary for 1P19
Entry DOI | 10.2210/pdb1p19/pdb |
Related | 1p17 1p18 1tc1 1tc2 |
Descriptor | hypoxanthine phosphoribosyltransferase, INOSINIC ACID (3 entities in total) |
Functional Keywords | transferase, glycosyltransferase, phosphoribosyltransferase, nucleotide metabolism, purine salvage, product complex |
Biological source | Trypanosoma cruzi |
Total number of polymer chains | 4 |
Total formula weight | 103774.44 |
Authors | Medrano, F.J.,Eakin, A.E.,Craig III, S.P. (deposition date: 2003-04-11, release date: 2004-05-18, Last modification date: 2024-02-14) |
Primary citation | Canyuk, B.,Medrano, F.J.,Wenck, M.A.,Focia, P.J.,Eakin, A.E.,Craig III, S.P. Interactions at the dimer interface influence the relative efficiencies for purine nucleotide synthesis and pyrophosphorolysis in a phosphoribosyltransferase. J.Mol.Biol., 335:905-921, 2004 Cited by PubMed: 14698288DOI: 10.1016/j.jmb.2003.11.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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