1P18
Hypoxanthine Phosphoribosyltransferase from Trypanosoma cruzi, K68R mutant, ternary substrates complex
Summary for 1P18
Entry DOI | 10.2210/pdb1p18/pdb |
Related | 1p17 1p19 1tc1 1tc2 |
Descriptor | hypoxanthine phosphoribosyltransferase, MAGNESIUM ION, 7-HYDROXY-PYRAZOLO[4,3-D]PYRIMIDINE, ... (5 entities in total) |
Functional Keywords | transferase, glycosyltransferase, phosphoribosyltransferase, nucleotide metabolism, purine salvage, ternary complex |
Biological source | Trypanosoma cruzi |
Total number of polymer chains | 2 |
Total formula weight | 52396.42 |
Authors | Canyuk, B.,Eakin, A.E.,Craig III, S.P. (deposition date: 2003-04-11, release date: 2004-05-18, Last modification date: 2024-02-14) |
Primary citation | Canyuk, B.,Medrano, F.J.,Wenck, M.A.,Focia, P.J.,Eakin, A.E.,Craig III, S.P. Interactions at the dimer interface influence the relative efficiencies for purine nucleotide synthesis and pyrophosphorolysis in a phosphoribosyltransferase J.Mol.Biol., 335:905-921, 2004 Cited by PubMed: 14698288DOI: 10.1016/j.jmb.2003.11.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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