2D8Q
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SOLUTION STRUCTURE OF THE MYND DOMAIN OF THE HUMAN ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 10
Descriptor:Zinc finger MYND domain containing protein 10, ZINC ION
Authors:Miyamoto, K., Kigawa, T., Tomizawa, T., Tochio, N., Sasagawa, A., Koshiba, S., Inoue, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-08
Release date:2006-06-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the MYND domain of the human zinc finger MYND domain-containing protein 10
To be Published
2DAN
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THE SOLUTION STRUCTURE OF THE MYND DOMAIN (LEU384-CYS430) OF HUMAN ZINC FINGER MYND DOMAIN CONTAINING PROTEIN 10
Descriptor:Zinc finger MYND domain containing protein 10, ZINC ION
Authors:Sasagawa, A., Miyamoto, K., Tochio, N., Koshiba, S., Inoue, M., Kigawa, T., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-14
Release date:2006-06-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of the MYND domain (LEU384-CYS430) of human Zinc finger MYND domain containing protein 10
To be Published
2DJ8
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SOLUTION STRUCTURE OF ZF-MYND DOMAIN OF PROTEIN CBFA2TI (PROTEIN MTG8)
Descriptor:Protein CBFA2T1, ZINC ION
Authors:Niraula, T.N., Sasagawa, A., Koshiba, S., Inoue, M., Kigawa, T., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-03-31
Release date:2006-10-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of zf-MYND Domain of Protein CBFA2TI (Protein MTG8)
To be published
2JW6
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SOLUTION STRUCTURE OF THE DEAF1 MYND DOMAIN
Descriptor:Deformed epidermal autoregulatory factor 1 homolog, ZINC ION
Authors:Spadaccini, R., Perrin, H., Bottomley, M., Ansieu, S., Sattler, M.
Deposit date:2007-10-08
Release date:2007-12-25
Last modified:2013-04-10
Method:SOLUTION NMR
Cite:Retraction notice to "Structure and functional analysis of the MYND domain" [J. Mol. Biol. (2006) 358, 498-508].
J.Mol.Biol., 376, 2008
2OD1
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SOLUTION STRUCTURE OF THE MYND DOMAIN FROM HUMAN AML1-ETO
Descriptor:Protein CBFA2T1, ZINC ION
Authors:Liu, Y.Z., Chen, W., Gaudet, J., Cheney, M.D., Roudaia, L., Cierpicki, T., Klet, R.C., Hartman, K., Laue, T.M., Speck, N.A., Bushweller, J.H.
Deposit date:2006-12-21
Release date:2007-06-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity.
Cancer Cell, 11, 2007
2ODD
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SOLUTION STRUCTURE OF THE MYND DOMAIN FROM AML1-ETO COMPLEXED WITH SMRT, A COREPRESSOR
Descriptor:SMRT, Protein CBFA2T1, ZINC ION
Authors:Liu, Y.Z., Chen, W., Gaudet, J., Cheney, M.D., Roudaia, L., Cierpicki, T., Klet, R.C., Hartman, K., Laue, T.M., Speck, N.A., Bushweller, J.H.
Deposit date:2006-12-22
Release date:2007-06-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity.
Cancer Cell, 11, 2007
4A24
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STRUCTURAL AND FUNCTIONAL ANALYSIS OF THE DEAF-1 AND BS69 MYND DOMAINS
Descriptor:DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG, ZINC ION
Authors:Kateb, F., Perrin, H., Tripsianes, K., Zou, P., Spadaccini, R., Bottomley, M., Bepperling, A., Ansieau, S., Sattler, M.
Deposit date:2011-09-22
Release date:2012-11-07
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:Structural and Functional Analysis of the Deaf-1 and Bs69 Mynd Domains.
Plos One, 8, 2013
3MEK
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CRYSTAL STRUCTURE OF HUMAN HISTONE-LYSINE N-METHYLTRANSFERASE SMYD3 IN COMPLEX WITH S-ADENOSYL-L-METHIONINE
Descriptor:SET and MYND domain-containing protein 3, ZINC ION, S-ADENOSYLMETHIONINE
Authors:Lam, R., Dombrovski, L., Li, Y., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Wu, H., Structural Genomics Consortium (SGC)
Deposit date:2010-03-31
Release date:2010-04-14
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Human Histone-Lysine N-methyltransferase SMYD3 in Complex with S-adenosyl-L-methionine
To be Published
3N71
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CRYSTAL STRUCTURE OF CARDIAC SPECIFIC HISTONE METHYLTRANSFERASE SMYD1
Descriptor:Histone lysine methyltransferase SmyD1, SINEFUNGIN, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Sirinupong, N., Yang, Z.
Deposit date:2010-05-26
Release date:2010-10-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Cardiac-specific Histone Methyltransferase SmyD1 Reveals Unusual Active Site Architecture.
J.Biol.Chem., 285, 2010
3OXF
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HUMAN LYSINE METHYLTRANSFERASE SMYD3 IN COMPLEX WITH ADOHCY (FORM I)
Descriptor:SET and MYND domain-containing protein 3, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
Authors:Xu, S., Wu, J., Sun, B., Zhong, C., Ding, J.
Deposit date:2010-09-21
Release date:2011-02-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Structural and biochemical studies of human lysine methyltransferase Smyd3 reveal the important functional roles of its post-SET and TPR domains and the regulation of its activity by DNA binding.
Nucleic Acids Res., 39, 2011
3OXG
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HUMAN LYSINE METHYLTRANSFERASE SMYD3 IN COMPLEX WITH ADOHCY (FORM III)
Descriptor:SET and MYND domain-containing protein 3, ZINC ION, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Xu, S., Wu, J., Sun, B., Zhong, C., Ding, J.
Deposit date:2010-09-21
Release date:2011-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Structural and biochemical studies of human lysine methyltransferase Smyd3 reveal the important functional roles of its post-SET and TPR domains and the regulation of its activity by DNA binding.
Nucleic Acids Res., 39, 2011
3OXL
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HUMAN LYSINE METHYLTRANSFERASE SMYD3 IN COMPLEX WITH ADOHCY (FORM II)
Descriptor:SET and MYND domain-containing protein 3, ZINC ION, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Xu, S., Wu, J., Sun, B., Zhong, C., Ding, J.
Deposit date:2010-09-21
Release date:2011-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural and biochemical studies of human lysine methyltransferase Smyd3 reveal the important functional roles of its post-SET and TPR domains and the regulation of its activity by DNA binding
Nucleic Acids Res., 39, 2011
3PDN
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CRYSTAL STRUCTURE OF SMYD3 IN COMPLEX WITH METHYLTRANSFERASE INHIBITOR SINEFUNGIN
Descriptor:SET and MYND domain-containing protein 3, SINEFUNGIN, GLYCEROL, ...
Authors:Sirinupong, N., Brunzelle, J., Yang, Z.
Deposit date:2010-10-23
Release date:2010-11-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Insights into the Autoinhibition and Posttranslational Activation of Histone Methyltransferase SmyD3.
J.Mol.Biol., 406, 2011
3QWP
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CRYSTAL STRUCTURE OF SET AND MYND DOMAIN CONTAINING 3; ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 1
Descriptor:SET and MYND domain-containing protein 3, ZINC ION, S-ADENOSYLMETHIONINE, ...
Authors:Dong, A., Dombrovski, L., Li, Y., Wernimont, A., Weigelt, J., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Wu, H., Structural Genomics Consortium (SGC)
Deposit date:2011-02-28
Release date:2011-04-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:The Crystal Structure of human Histone-lysine N-methyltransferase SMYD3
To be Published
3QWV
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CRYSTAL STRUCTURE OF HISTONE LYSINE METHYLTRANSFERASE SMYD2 IN COMPLEX WITH THE COFACTOR PRODUCT ADOHCY
Descriptor:SET and MYND domain-containing protein 2, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
Authors:Jiang, Y., Sirinupong, N., Brunzelle, J., Yang, Z.
Deposit date:2011-02-28
Release date:2011-07-06
Last modified:2012-03-21
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Crystal structures of histone and p53 methyltransferase SmyD2 reveal a conformational flexibility of the autoinhibitory C-terminal domain.
Plos One, 6, 2011
3QWW
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CRYSTAL STRUCTURE OF HISTONE LYSINE METHYLTRANSFERASE SMYD2 IN COMPLEX WITH THE METHYLTRANSFERASE INHIBITOR SINEFUNGIN
Descriptor:SET and MYND domain-containing protein 2, SINEFUNGIN, ZINC ION
Authors:Jiang, Y., Sirinupong, N., Brunzelle, J., Yang, Z.
Deposit date:2011-02-28
Release date:2011-07-06
Last modified:2012-03-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of histone and p53 methyltransferase SmyD2 reveal a conformational flexibility of the autoinhibitory C-terminal domain.
Plos One, 6, 2011
3RIB
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HUMAN LYSINE METHYLTRANSFERASE SMYD2 IN COMPLEX WITH ADOHCY
Descriptor:N-lysine methyltransferase SMYD2, ZINC ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Xu, S., Zhang, T., Zhong, C., Ding, J.
Deposit date:2011-04-13
Release date:2011-07-20
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structure of human lysine methyltransferase Smyd2 reveals insights into the substrate divergence in Smyd proteins
J Mol Cell Biol, 3, 2011
3RU0
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COCRYSTAL STRUCTURE OF HUMAN SMYD3 WITH INHIBITOR SINEFUNGIN BOUND
Descriptor:SET and MYND domain-containing protein 3, SINEFUNGIN, ZINC ION
Authors:Foreman, K.W., Brown, M., Park, F., Emtage, S., Harriss, J., Das, C., Zhu, L., Crew, A., Arnold, L., Shaaban, S., Tucker, P.
Deposit date:2011-05-04
Release date:2011-05-18
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (1.849 Å)
Cite:Structural and Functional Profiling of the Human Histone Methyltransferase SMYD3.
Plos One, 6, 2011
3S7B
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STRUCTURAL BASIS OF SUBSTRATE METHYLATION AND INHIBITION OF SMYD2
Descriptor:N-lysine methyltransferase SMYD2, S-ADENOSYLMETHIONINE, (R,R)-2,3-BUTANEDIOL, ...
Authors:Ferguson, A.D.
Deposit date:2011-05-26
Release date:2011-08-10
Last modified:2011-09-21
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural Basis of Substrate Methylation and Inhibition of SMYD2.
Structure, 19, 2011
3S7D
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STRUCTURAL BASIS OF SUBSTRATE METHYLATION AND INHIBITION OF SMYD2
Descriptor:N-lysine methyltransferase SMYD2, Monomethylated p53 peptide, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Ferguson, A.D.
Deposit date:2011-05-26
Release date:2011-08-10
Last modified:2011-09-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of Substrate Methylation and Inhibition of SMYD2.
Structure, 19, 2011
3S7F
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STRUCTURAL BASIS OF SUBSTRATE METHYLATION AND INHIBITION OF SMYD2
Descriptor:N-lysine methyltransferase SMYD2, p53 peptide, S-ADENOSYLMETHIONINE, ...
Authors:Ferguson, A.D.
Deposit date:2011-05-26
Release date:2011-08-10
Last modified:2011-09-21
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural Basis of Substrate Methylation and Inhibition of SMYD2.
Structure, 19, 2011
3S7J
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STRUCTURAL BASIS OF SUBSTRATE METHYLATION AND INHIBITION OF SMYD2
Descriptor:N-lysine methyltransferase SMYD2, S-ADENOSYLMETHIONINE, ZINC ION
Authors:Ferguson, A.D.
Deposit date:2011-05-26
Release date:2011-08-10
Last modified:2011-09-21
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Structural Basis of Substrate Methylation and Inhibition of SMYD2.
Structure, 19, 2011
3TG4
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STRUCTURE OF SMYD2 IN COMPLEX WITH SAM
Descriptor:N-lysine methyltransferase SMYD2, S-ADENOSYLMETHIONINE, ZINC ION, ...
Authors:Zhao, K., Wang, L.
Deposit date:2011-08-17
Release date:2011-08-31
Last modified:2011-09-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of human SMYD2 reveals the basis of p53 tumor suppressor methylation
J.Biol.Chem., 2011
3TG5
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STRUCTURE OF SMYD2 IN COMPLEX WITH P53 AND SAH
Descriptor:N-lysine methyltransferase SMYD2, Cellular tumor antigen p53, GLYCEROL, ...
Authors:Zhao, K., Wang, L.
Deposit date:2011-08-17
Release date:2011-08-31
Last modified:2011-09-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of human SMYD2 reveals the basis of p53 tumor suppressor methylation
J.Biol.Chem., 2011
4O6F
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STRUCTURAL BASIS OF ESTROGEN RECEPTOR ALPHA METHYLATION MEDIATED BY HISTONE METHYLTRANSFERASE SMYD2
Descriptor:N-lysine methyltransferase SMYD2, Estrogen receptor, ZINC ION, ...
Authors:Jiang, Y., Trescott, L., Holcomb, J., Brunzelle, J., Sirinupong, N., Shi, X., Yang, Z.
Deposit date:2013-12-20
Release date:2014-03-26
Last modified:2014-10-08
Method:X-RAY DIFFRACTION (2.822 Å)
Cite:Structural Insights into Estrogen Receptor alpha Methylation by Histone Methyltransferase SMYD2, a Cellular Event Implicated in Estrogen Signaling Regulation.
J.Mol.Biol., 426, 2014
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