Summary for 8OWO
| Entry DOI | 10.2210/pdb8owo/pdb |
| Related | 7QLB 7QNR 7QNU |
| Descriptor | Histone-lysine N-methyltransferase SMYD3, S-ADENOSYLMETHIONINE, ZINC ION, ... (6 entities in total) |
| Functional Keywords | methyltransferase, epigenetic, oncogen, histone, transferase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 50266.28 |
| Authors | Lund, B.A.,Cederfelt, D.,Dobritzsch, D. (deposition date: 2023-04-28, release date: 2023-08-30, Last modification date: 2024-07-03) |
| Primary citation | FitzGerald, E.A.,Cederfelt, D.,Lund, B.A.,Myers, N.E.M.,Zhang, H.,Dobritzsch, D.,Danielson, U.H. Identification of fragments targeting SMYD3 using highly sensitive kinetic and multiplexed biosensor-based screening. Rsc Med Chem, 15:1982-1990, 2024 Cited by PubMed: 38911161DOI: 10.1039/d4md00093e PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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