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8OWO

SMYD3 in complex with fragment FL01507

Replaces:  7QA6
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Histone-lysine N-methyltransferase SMYD3polymer43149460.41UniProt (Q9H7B4)
Pfam (PF00856)
Pfam (PF01753)
Homo sapiens (human)SET and MYND domain-containing protein 3,Zinc finger MYND domain-containing protein 1
2B
(A)
S-ADENOSYLMETHIONINEnon-polymer398.41Chemie (SAM)
3C, D, E
(A)
ZINC IONnon-polymer65.43Chemie (ZN)
4F
(A)
3-oxidanylbenzenecarbonitrilenon-polymer119.11Chemie (9W9)
5G
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
6H
(A)
waterwater18.0482Chemie (HOH)
Sequence modifications
A: 1 - 428 (UniProt: Q9H7B4)
PDBExternal DatabaseDetails
Gly -2-expression tag
Ser -1-expression tag
His 0-expression tag
Asn 13Lys 13engineered mutation
Arg 140Lys 140engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight49460.4
Non-Polymers*Number of molecules6
Total formula weight805.9
All*Total formula weight50266.3
*Water molecules are not included.

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PDB entries from 2025-12-17

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