7QLB
SMYD3 in complex with fragment FL06268
Summary for 7QLB
Entry DOI | 10.2210/pdb7qlb/pdb |
Related | 7QA6 |
Descriptor | Histone-lysine N-methyltransferase SMYD3, ZINC ION, 1-methylimidazole-4-sulfonamide, ... (5 entities in total) |
Functional Keywords | methyltransferase, epigenetic, oncogen, histone, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 50377.43 |
Authors | Lund, B.A.,Cederfelt, D.,Dobritzsch, D. (deposition date: 2021-12-20, release date: 2023-03-29, Last modification date: 2024-04-24) |
Primary citation | FitzGerald, E.A.,Cederfelt, D.,Lund, B.A.,Myers, N.,Zhang, H.,Dobritzsch, D.,Danielson, H. Identification of fragments targeting SMYD3 using highly sensitive kinetic and multiplexed biosensor-based screening Rsc Med Chem, 2024 Cited by DOI: 10.1039/D4MD00093EPDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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