7QLB

SMYD3 in complex with fragment FL06268

Summary for 7QLB

Entry DOI	10.2210/pdb7qlb/pdb
Related	7QA6
Descriptor	Histone-lysine N-methyltransferase SMYD3, ZINC ION, 1-methylimidazole-4-sulfonamide, ... (5 entities in total)
Functional Keywords	methyltransferase, epigenetic, oncogen, histone, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	50377.43
Authors	Lund, B.A.,Cederfelt, D.,Dobritzsch, D. (deposition date: 2021-12-20, release date: 2023-03-29, Last modification date: 2024-04-24)
Primary citation	FitzGerald, E.A.,Cederfelt, D.,Lund, B.A.,Myers, N.,Zhang, H.,Dobritzsch, D.,Danielson, H. Identification of fragments targeting SMYD3 using highly sensitive kinetic and multiplexed biosensor-based screening Rsc Med Chem, 2024 Cited by DOI: 10.1039/D4MD00093E PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation