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1H6G
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BU of 1h6g by Molmil
alpha-catenin M-domain
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ALPHA-1 CATENIN, CALCIUM ION, ...
Authors:Yang, J, Dokurno, P, Tonks, N.K, Barford, D.
Deposit date:2001-06-14
Release date:2001-08-07
Last modified:2016-02-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of the M-Fragment of Alpha-Catenin: Implications for Modulation of Cell Adhesion.
Embo J., 20, 2001
1L7C
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BU of 1l7c by Molmil
alpha-catenin fragment, residues 385-651
Descriptor: Alpha E-catenin
Authors:Pokutta, S, Drees, F, Takai, Y, Nelson, W.J, Weis, W.I.
Deposit date:2002-03-14
Release date:2002-06-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Biochemical and structural definition of the l-afadin- and actin-binding sites of alpha-catenin.
J.Biol.Chem., 277, 2002
1QKR
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Crystal structure of the vinculin tail and a pathway for activation
Descriptor: SULFATE ION, VINCULIN
Authors:Bakolitsa, C, De Pereda, J.M, Bagshaw, C.R, Critchley, D.R, Liddington, R.C.
Deposit date:1999-08-04
Release date:2000-08-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the Vinculin Tail and a Pathway for Activation
Cell(Cambridge,Mass.), 99, 1999
1RKC
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Human vinculin head (1-258) in complex with talin's vinculin binding site 3 (residues 1944-1969)
Descriptor: Talin, Vinculin
Authors:Izard, T, Evans, G, Borgon, R.A, Rush, C.L, Bricogne, G, Bois, P.R.
Deposit date:2003-11-21
Release date:2004-01-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Vinculin activation by talin through helical bundle conversion
Nature, 427, 2004
1RKE
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Human vinculin head (1-258) in complex with human vinculin tail (879-1066)
Descriptor: VCL protein, Vinculin
Authors:Izard, T, Evans, G, Borgon, R.A, Rush, C.L, Bricogne, G, Bois, P.R.
Deposit date:2003-11-21
Release date:2004-01-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Vinculin activation by talin through helical bundle conversion
Nature, 427, 2004
1ST6
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BU of 1st6 by Molmil
Crystal structure of a cytoskeletal protein
Descriptor: Vinculin
Authors:Bakolitsa, C, Liddington, R.C.
Deposit date:2004-03-25
Release date:2004-08-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for vinculin activation at sites of cell adhesion.
Nature, 430, 2004
1SYQ
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BU of 1syq by Molmil
Human vinculin head domain VH1, residues 1-258, in complex with human talin's vinculin binding site 1, residues 607-636
Descriptor: Talin 1, vinculin isoform VCL
Authors:Izard, T, Vonrhein, C.
Deposit date:2004-04-01
Release date:2004-07-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural basis for amplifying vinculin activation by talin
J.Biol.Chem., 279, 2004
1T01
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BU of 1t01 by Molmil
Vinculin complexed with the VBS1 helix from talin
Descriptor: Talin 1, unnamed protein product
Authors:Papagrigoriou, E, Gingras, A.R, Barsukov, I.L, Critchley, D.R, Emsley, J.
Deposit date:2004-04-07
Release date:2004-08-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle
Embo J., 23, 2004
1TR2
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BU of 1tr2 by Molmil
Crystal structure of human full-length vinculin (residues 1-1066)
Descriptor: VINCULIN ISOFORM 1
Authors:Borgon, R.A, Vonrhein, C, Bricogne, G, Bois, P.R, Izard, T.
Deposit date:2004-06-19
Release date:2005-11-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of Human Vinculin
Structure, 12, 2004
1U6H
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BU of 1u6h by Molmil
Vinculin head (0-258) in complex with the talin vinculin binding site 2 (849-879)
Descriptor: Talin, Vinculin
Authors:Fillingham, I, Gingras, A.R, Papagrigoriou, E, Patel, B, Emsley, J, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L.
Deposit date:2004-07-30
Release date:2005-01-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:A vinculin binding domain from the talin rod unfolds to form a complex with the vinculin head.
Structure, 13, 2005
1XWJ
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BU of 1xwj by Molmil
Vinculin head (1-258) in complex with the talin vinculin binding site 3 (1945-1969)
Descriptor: Talin, Vinculin
Authors:Gingras, A.R, Papagrigoriou, E, Barsukov, I.L, Critchley, D.R, Emsley, J.
Deposit date:2004-11-01
Release date:2005-10-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and Dynamic Characterization of a Vinculin Binding Site in the Talin Rod
Biochemistry, 45, 2006
1YDI
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BU of 1ydi by Molmil
Human Vinculin Head Domain (VH1, 1-258) in Complex with Human Alpha-Actinin's Vinculin-Binding Site (Residues 731-760)
Descriptor: Alpha-actinin 4, vinculin isoform VCL
Authors:Izard, T.
Deposit date:2004-12-23
Release date:2005-07-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Dynamics of {alpha}-Actinin-Vinculin Interactions.
Mol.Cell.Biol., 14, 2005
1ZVZ
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BU of 1zvz by Molmil
Vinculin Head (0-258) in Complex with the Talin Rod Residue 820-844
Descriptor: Talin 1, Vinculin
Authors:Gingras, A.R, Ziegler, W.H, Barsukov, I.L, Roberts, G.C, Critchley, D.R, Emsley, J.
Deposit date:2005-06-03
Release date:2005-09-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod
J.Biol.Chem., 280, 2005
1ZW2
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BU of 1zw2 by Molmil
Vinculin Head (0-258) in Complex with the Talin Rod residues 2345-2369
Descriptor: Vinculin, talin
Authors:Gingras, A.R, Ziegler, W.H, Barsukov, I.L, Roberts, G.C, Critchley, D.R, Emsley, J.
Deposit date:2005-06-03
Release date:2005-09-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod
J.Biol.Chem., 280, 2005
1ZW3
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BU of 1zw3 by Molmil
Vinculin Head (0-258) in Complex with the Talin Rod residues 1630-1652
Descriptor: Talin 1, Vinculin
Authors:Gingras, A.R, Ziegler, W.H, Barsukov, I.L, Roberts, G.C, Critchley, D.R, Emsley, J.
Deposit date:2005-06-03
Release date:2005-09-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod
J.Biol.Chem., 280, 2005
2GDC
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BU of 2gdc by Molmil
Structure of Vinculin VD1 / IpaA560-633 complex
Descriptor: Invasin ipaA, Vinculin
Authors:Hamiaux, C, van Eerde, A, Parsot, C, Broos, J, Dijkstra, B.W.
Deposit date:2006-03-15
Release date:2006-08-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Structural mimicry for vinculin activation by IpaA, a virulence factor of Shigella flexneri.
Embo Rep., 7, 2006
2GWW
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BU of 2gww by Molmil
Human vinculin (head domain, Vh1, residues 1-258) in complex with Shigella's IpaA vinculin binding site (residues 602-633)
Descriptor: IpaA, vinculin
Authors:Izard, T.
Deposit date:2006-05-07
Release date:2006-11-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Shigella applies molecular mimicry to subvert vinculin and invade host cells.
J.Cell Biol., 175, 2006
2HSQ
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BU of 2hsq by Molmil
Human vinculin (head domain, Vh1, residues 1-258) in complex with Shigella's IpaA vinculin binding site 2 (residues 565-587)
Descriptor: Invasin ipaA, Vinculin
Authors:Izard, T.
Deposit date:2006-07-22
Release date:2006-11-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.97 Å)
Cite:Shigella applies molecular mimicry to subvert vinculin and invade host cells.
J.Cell Biol., 175, 2006
2IBF
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BU of 2ibf by Molmil
Human vinculin's head domain (Vh1, residues 1-258) in complex with two vinculin binding sites of Shigella flexneri's IpaA (residues 565-587)
Descriptor: Invasin ipaA, Vinculin
Authors:Izard, T.
Deposit date:2006-09-11
Release date:2007-09-18
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Vinculin binding in its closed conformation by a helix addition mechanism.
Embo J., 26, 2007
3H2U
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BU of 3h2u by Molmil
Human raver1 RRM1, RRM2, and RRM3 domains in complex with human vinculin tail domain Vt
Descriptor: Raver-1, Vinculin
Authors:Lee, J.H, Rangarajan, E.S, Yogesha, S.D, Izard, T.
Deposit date:2009-04-14
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Raver1 interactions with vinculin and RNA suggest a feed-forward pathway in directing mRNA to focal adhesions
Structure, 17, 2009
3H2V
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BU of 3h2v by Molmil
Human raver1 RRM1 domain in complex with human vinculin tail domain Vt
Descriptor: Raver-1, Vinculin
Authors:Lee, J.H, Rangarajan, E.S, Yogesha, S.D, Izard, T.
Deposit date:2009-04-14
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Raver1 interactions with vinculin and RNA suggest a feed-forward pathway in directing mRNA to focal adhesions
Structure, 17, 2009
3JBI
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BU of 3jbi by Molmil
MDFF model of the vinculin tail domain bound to F-actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Kim, L.Y, Thompson, P.M, Lee, H.T, Pershad, M, Campbell, S.L, Alushin, G.M.
Deposit date:2015-09-02
Release date:2015-11-04
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:The Structural Basis of Actin Organization by Vinculin and Metavinculin.
J.Mol.Biol., 428, 2016
3JBK
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BU of 3jbk by Molmil
Cryo-EM reconstruction of the metavinculin-actin interface
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Kim, L.Y, Thompson, P.M, Lee, H.T, Pershad, M, Campbell, S.L, Alushin, G.M.
Deposit date:2015-09-03
Release date:2015-11-04
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (8.2 Å)
Cite:The Structural Basis of Actin Organization by Vinculin and Metavinculin.
J.Mol.Biol., 428, 2016
3MYI
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BU of 3myi by Molmil
Human metavinculin tail domain
Descriptor: Vinculin
Authors:Izard, T, Rangarajan, E.S.
Deposit date:2010-05-10
Release date:2010-05-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A helix replacement mechanism directs metavinculin functions.
Plos One, 5, 2010
3RF3
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BU of 3rf3 by Molmil
Shigella IpaA-VBS3 in complex with human vinculin
Descriptor: CACODYLATE ION, Invasin ipaA, Vinculin
Authors:Park, H, Sharff, A, Izard, T.
Deposit date:2011-04-05
Release date:2011-04-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Novel vinculin binding site of the IpaA invasin of Shigella.
J.Biol.Chem., 286, 2011

 

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