6GVY
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MUTANT M16A OF RNA DEPENDENT RNA POLYMERASE 3D FROM FOOT-AND-MOUTH DISEASE VIRUS COMPLEXED WITH AN TEMPLATE -PRIMER RNA
Descriptor:Genome polyprotein, RNA (5'-R(P*CP*CP*GP*GP*G)-3'), RNA (5'-R(P*CP*UP*CP*CP*CP*GP*GP*G)-3'), ...
Authors:Verdaguer, N., Ferrer-Orta, C.
Deposit date:2018-06-21
Release date:2018-08-01
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis.
J. Virol., 92, 2018
6GVV
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MUTANT M16A OF RNA DEPENDENT RNA POLYMERASE 3D FROM FOOT-AND-MOUTH DISEASE VIRUS
Descriptor:RNA polymerase 3D, GLYCEROL
Authors:Verdaguer, N., Ferrer Orta, C.
Deposit date:2018-06-21
Release date:2018-08-01
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Contribution of a multifunctional polymerase region of foot-and-mouth disease virus to lethal mutagenesis
To Be Published
5Y6Z
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CRYSTAL STRUCTURE OF THE COXSACKIEVIRUS A16 POLYMERASE ELONGATION COMPLEX
Descriptor:Genome polyprotein, Template RNA (33-MER), Product RNA (14-MER), ...
Authors:Bi, P., Shu, B., Gong, P.
Deposit date:2017-08-15
Release date:2017-12-27
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the coxsackievirus A16 RNA-dependent RNA polymerase elongation complex reveals novel features in motif A dynamics
Virol Sin, 32, 2017
5Y3D
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STRUCTURAL INSIGHT INTO THE INTERACTION BETWEEN RNA POLYMERASE AND VPG FOR NOROVIRUS REPLICATION
Descriptor:RNA-dependent RNA polymerase, viral protein genome-linked (VPg)
Authors:Kim, K.H., Lee, J.-H., Seok, J.H.
Deposit date:2017-07-28
Release date:2018-07-18
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:Insight Into the Interaction Between RNA Polymerase and VPg for Murine Norovirus Replication.
Front Microbiol, 9, 2018
5XE0
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CRYSTAL STRUCTURE OF EV-D68-3DPOL IN COMPLEX WITH GTP
Descriptor:Genome polyprotein, GUANOSINE-5'-TRIPHOSPHATE
Authors:Xie, W., Wang, C., Wang, Z., Li, Q., Wang, C.
Deposit date:2017-03-30
Release date:2017-06-28
Last modified:2018-01-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure and Thermostability Characterization of Enterovirus D68 3Dpol
J. Virol., 91, 2017
5TSN
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CRYSTAL STRUCTURES OF NORWALK VIRUS POLYMERASE BOUND TO AN RNA PRIMER-TEMPLATE DUPLEX
Descriptor:Norwalk virus polymerase, RNA (5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3'), MANGANESE (II) ION
Authors:Shaik, M.M., Ng, K.K.
Deposit date:2016-10-30
Release date:2017-04-12
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Norovirus RNA-dependent RNA polymerase: A computational study of metal-binding preferences.
Proteins, 85, 2017
5N95
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TETRAGONAL STRUCTURE OF MUTANT V173I OF 3D POLYMERASE FROM FOOT-AND-MOUTH DISEASE VIRUS
Descriptor:3D polymerase, TRIPHOSPHATE
Authors:Ferrer-Orta, C., Verdaguer, N.
Deposit date:2017-02-24
Release date:2017-05-10
Last modified:2017-05-31
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular and Functional Bases of Selection against a Mutation Bias in an RNA Virus.
Genome Biol Evol, 9, 2017
5N8X
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TRIGONAL STRUCTURE OF MUTANT V173I OF 3D POLYMERASE FROM FOOT-AND-MOUTH DISEASE VIRUS
Descriptor:3D polymerase, MANGANESE (II) ION, GLYCEROL
Authors:Ferrer-Orta, C., Verdaguer, N.
Deposit date:2017-02-24
Release date:2017-05-10
Last modified:2017-05-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular and Functional Bases of Selection against a Mutation Bias in an RNA Virus.
Genome Biol Evol, 9, 2017
5JXS
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MUTANT GC216/7AA OF 3D POLYMERASE FROM FOOT-AND-MOUTH DISEASE VIRUS
Descriptor:RNA dependent RNA polymerase, RNA Template, RNA Primer, ...
Authors:Verdaguer, N., Ferrer-Orta, C.
Deposit date:2016-05-13
Release date:2016-06-01
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Both cis and trans Activities of Foot-and-Mouth Disease Virus 3D Polymerase Are Essential for Viral RNA Replication.
J.Virol., 90, 2016
5I62
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CRYSTAL STRUCTURE OF THE INSERTION LOOP DELETION MUTANT OF THE RNA-DEPENDENT RNA POLYMERASE OF A HUMAN PICORBIRNAVIRUS
Descriptor:Potential RNA-dependent RNA polymerase
Authors:Collier, A.M., Guo, Y.R., Tao, Y.J.
Deposit date:2016-02-15
Release date:2016-03-16
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Initiation of RNA Polymerization and Polymerase Encapsidation by a Small dsRNA Virus.
Plos Pathog., 12, 2016
5I61
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CRYSTAL STRUCTURE OF THE RNA-DEPENDENT RNA POLYMERASE OF A HUMAN PICORBIRNAVIRUS
Descriptor:Potential RNA-dependent RNA polymerase
Authors:Collier, A.M., Guo, Y.R., Tao, Y.J.
Deposit date:2016-02-15
Release date:2016-03-16
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Initiation of RNA Polymerization and Polymerase Encapsidation by a Small dsRNA Virus.
Plos Pathog., 12, 2016
5FJ7
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STRUCTURE OF THE P2 POLYMERASE INSIDE IN VITRO ASSEMBLED BACTERIOPHAGE PHI6 POLYMERASE COMPLEX, WITH P1 INCLUDED
Descriptor:MAJOR INNER PROTEIN P1, RNA-DIRECTED RNA POLYMERASE, MANGANESE (II) ION
Authors:Ilca, S., Kotecha, A., Sun, X., Poranen, M.P., Stuart, D.I., Huiskonen, J.T.
Deposit date:2015-10-06
Release date:2015-11-04
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:Localized Reconstruction of Subunits from Electron Cryomicroscopy Images of Macromolecular Complexes.
Nat.Commun., 6, 2015
5FJ6
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STRUCTURE OF THE P2 POLYMERASE INSIDE IN VITRO ASSEMBLED BACTERIOPHAGE PHI6 POLYMERASE COMPLEX
Descriptor:RNA-DIRECTED RNA POLYMERASE, MANGANESE (II) ION
Authors:Ilca, S., Kotecha, A., Sun, X., Poranen, M.P., Stuart, D.I., Huiskonen, J.T.
Deposit date:2015-10-06
Release date:2015-11-04
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:Localized Reconstruction of Subunits from Electron Cryomicroscopy Images of Macromolecular Complexes.
Nat.Commun., 6, 2015
5F8N
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ENTEROVIRUS 71 POLYMERASE ELONGATION COMPLEX (C3S6 FORM)
Descriptor:Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*CP*U)-3'), ...
Authors:Shu, B., Gong, P.
Deposit date:2015-12-09
Release date:2016-06-22
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2.484 Å)
Cite:Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
5F8M
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ENTEROVIRUS 71 POLYMERASE ELONGATION COMPLEX (C3S4/5 FORM)
Descriptor:Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*CP*U)-3'), ...
Authors:Shu, B., Gong, P.
Deposit date:2015-12-09
Release date:2016-06-22
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
5F8L
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ENTEROVIRUS 71 POLYMERASE ELONGATION COMPLEX (C3S1 FORM)
Descriptor:Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*C)-3'), ...
Authors:Shu, B., Gong, P.
Deposit date:2015-12-09
Release date:2016-06-22
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2.812 Å)
Cite:Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
5F8J
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ENTEROVIRUS 71 POLYMERASE ELONGATION COMPLEX (C1S4 FORM)
Descriptor:Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*C)-3'), ...
Authors:Shu, B., Gong, P.
Deposit date:2015-12-09
Release date:2016-06-22
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2.675 Å)
Cite:Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
5F8I
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ENTEROVIRUS 71 POLYMERASE ELONGATION COMPLEX (C1S2/3 FORM)
Descriptor:Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*A)-3'), ...
Authors:Shu, B., Gong, P.
Deposit date:2015-12-09
Release date:2016-06-22
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2.503 Å)
Cite:Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
5F8H
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ENTEROVIRUS 71 POLYMERASE ELONGATION COMPLEX (C1S1/2 FORM)
Descriptor:Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*A)-3'), ...
Authors:Shu, B., Gong, P.
Deposit date:2015-12-09
Release date:2016-06-22
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
5F8G
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ENTEROVIRUS 71 POLYMERASE ELONGATION COMPLEX (C1S1 FORM)
Descriptor:Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*A)-3'), ...
Authors:Shu, B., Gong, P.
Deposit date:2015-12-09
Release date:2016-06-22
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
4ZPD
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COXSACKIEVIRUS B3 POLYMERASE - A345V MUTANT
Descriptor:RNA-directed RNA polymerase
Authors:Peersen, O.B., McDonald, S.M.
Deposit date:2015-05-07
Release date:2016-05-11
Last modified:2016-07-13
Method:X-RAY DIFFRACTION (1.797 Å)
Cite:Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
4ZPC
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COXSACKIEVIRUS B3 POLYMERASE - A341G MUTANT
Descriptor:RNA-dependent RNA polymerase
Authors:Peersen, O.B., McDonald, S.M.
Deposit date:2015-05-07
Release date:2016-05-11
Last modified:2016-07-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
4ZPB
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COXSACKIEVIRUS B3 POLYMERASE - F364W MUTANT
Descriptor:RNA-directed RNA polymerase
Authors:Peersen, O.B., McDonald, S.M.
Deposit date:2015-05-07
Release date:2016-05-11
Last modified:2016-07-13
Method:X-RAY DIFFRACTION (1.797 Å)
Cite:Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
4ZPA
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COXSACKIEVIRUS B3 POLYMERASE - F364Y MUTANT
Descriptor:RNA-directed RNA polymerase, SULFATE ION
Authors:Peersen, O.B., McDonald, S.M.
Deposit date:2015-05-07
Release date:2016-05-11
Last modified:2016-07-13
Method:X-RAY DIFFRACTION (2.665 Å)
Cite:Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
4ZP9
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COXSACKIEVIRUS B3 POLYMERASE - F364I MUTANT
Descriptor:RNA-dependent RNA polymerase
Authors:Peersen, O.B., McDonald, S.M.
Deposit date:2015-05-07
Release date:2016-05-11
Last modified:2016-07-13
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
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