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8RQ3
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Cryo-em structure of the rat Multidrug resistance-associated protein 2 (rMrp2) in an autoinhibited state (nucleotide-free)
Descriptor: ATP-binding cassette sub-family C member 2
Authors:Mazza, T, Beis, K.
Deposit date:2024-01-17
Release date:2024-02-14
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Structural basis for the modulation of MRP2 activity by phosphorylation and drugs.
Nat Commun, 15, 2024
8RQ4
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Cryo-em structure of the rat Multidrug resistance-associated protein 2 (rMrp2) in complex with probenecid
Descriptor: 4-(dipropylsulfamoyl)benzoic acid, ATP-binding cassette sub-family C member 2, CHOLESTEROL HEMISUCCINATE
Authors:Mazza, T, Beis, K.
Deposit date:2024-01-17
Release date:2024-02-14
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Structural basis for the modulation of MRP2 activity by phosphorylation and drugs.
Nat Commun, 15, 2024
8WP0
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Structure of the Arabidopsis E529Q/E1174Q ABCB19 in the ATP bound state
Descriptor: ABC transporter B family member 19, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Ying, W, Wei, H, Liu, X, Sun, L.
Deposit date:2023-10-08
Release date:2024-03-13
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export.
Science, 383, 2024
8WOO
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Structure of the wild-type Arabidopsis ABCB19 in the brassinolide and AMP-PNP bound state
Descriptor: ABC transporter B family member 19, Brassinolide, MAGNESIUM ION, ...
Authors:Ying, W, Wei, H, Liu, X, Sun, L.
Deposit date:2023-10-07
Release date:2024-03-13
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export.
Science, 383, 2024
8WOM
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Structure of the wild-type Arabidopsis ABCB19 in the brassinolide-bound state
Descriptor: ABC transporter B family member 19, Brassinolide
Authors:Ying, W, Wei, H, Liu, X, Sun, L.
Deposit date:2023-10-07
Release date:2024-03-13
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export.
Science, 383, 2024
8WOI
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Structure of the wild-type Arabidopsis ABCB19 in the apo state
Descriptor: ABC transporter B family member 19
Authors:Ying, W, Wei, H, Liu, X, Sun, L.
Deposit date:2023-10-07
Release date:2024-03-13
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export.
Science, 383, 2024
8QOE
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Inward-facing conformation of the ABC transporter BmrA
Descriptor: Multidrug resistance ABC transporter ATP-binding/permease protein BmrA
Authors:Di Cesare, M, Kaplan, E, Valimehr, S, Hanssen, E, Orelle, C, Jault, J.M.
Deposit date:2023-09-28
Release date:2023-12-20
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:The transport activity of the multidrug ABC transporter BmrA does not require a wide separation of the nucleotide-binding domains.
J.Biol.Chem., 300, 2023
8UBR
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Complex of the phosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) with CFTRinh-172 and ATP/Mg
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 4-[(Z)-{(3M)-4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene}methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Young, P.G, Fiedorczuk, K, Chen, J.
Deposit date:2023-09-24
Release date:2024-02-21
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural basis for CFTR inhibition by CFTR inh -172.
Proc.Natl.Acad.Sci.USA, 121, 2024
8K7C
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Outward-facing structure of human ABCB6 W546A mutant (ADP/VO4-bound)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family B member 6, MAGNESIUM ION, ...
Authors:Jin, M.S, Lee, S.S, Park, J.G, Jang, E, Choi, S.H, Kim, S, Kim, J.W.
Deposit date:2023-07-26
Release date:2023-10-04
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:W546 stacking disruption traps the human porphyrin transporter ABCB6 in an outward-facing transient state.
Commun Biol, 6, 2023
8K7B
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post-occluded structure of human ABCB6 W546A mutant (ADP/VO4-bound)
Descriptor: (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, ADP ORTHOVANADATE, ATP-binding cassette sub-family B member 6, ...
Authors:Jin, M.S, Lee, S.S, Park, J.G, Jang, E, Choi, S.H, Kim, S, Kim, J.W.
Deposit date:2023-07-26
Release date:2023-10-04
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:W546 stacking disruption traps the human porphyrin transporter ABCB6 in an outward-facing transient state.
Commun Biol, 6, 2023
8K7A
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Cryo-EM structure of nucleotide-bound ComA E647Q mutant with Mg2+
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Transport/processing ATP-binding protein ComA
Authors:Yu, L, Xin, X, Min, L.
Deposit date:2023-07-26
Release date:2023-10-11
Last modified:2023-11-29
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis of peptide secretion for Quorum sensing by ComA
Nat Commun, 14, 2023
8PX9
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Structure of the antibacterial peptide ABC transporter McjD, solved at wavelength 2.75 A
Descriptor: MAGNESIUM ION, Microcin-J25 export ATP-binding/permease protein McjD, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:El Omari, K, Duman, R, Mykhaylyk, V, Orr, C, Bountra, K, Beis, K, Wagner, A.
Deposit date:2023-07-22
Release date:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Experimental phasing opportunities for macromolecular crystallography at very long wavelengths.
Commun Chem, 6, 2023
8TI1
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Cryo-EM structure of a SUR1/Kir6.2-Q52R ATP-sensitive potassium channel in the presence of PIP2 in the open conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-sensitive inward rectifier potassium channel 11, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ...
Authors:Driggers, C.M, Shyng, S.-L.
Deposit date:2023-07-18
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure of an open K ATP channel reveals tandem PIP 2 binding sites mediating the Kir6.2 and SUR1 regulatory interface.
Nat Commun, 15, 2024
8TI2
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Cryo-EM structure of a SUR1/Kir6.2-Q52R ATP-sensitive potassium channel in the presence of PIP2 in the open conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-sensitive inward rectifier potassium channel 11, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ...
Authors:Driggers, C.M, Shyng, S.-L.
Deposit date:2023-07-18
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Structure of an open K ATP channel reveals tandem PIP 2 binding sites mediating the Kir6.2 and SUR1 regulatory interface.
Nat Commun, 15, 2024
8K4B
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Cryo-EM structure of nucleotide-bound ComA with ZinC ion
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Competence factor transporting ATP-binding protein/permease ComA, ZINC ION
Authors:Yu, L, Xin, X, Min, L, Feng, H.
Deposit date:2023-07-17
Release date:2023-10-11
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of peptide secretion for Quorum sensing by ComA
Nat Commun, 14, 2023
8JY5
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Cryo-EM structure of human ABC transporter ABCC2 in apo" state
Descriptor: ATP-binding cassette sub-family C member 2
Authors:Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z.
Deposit date:2023-07-03
Release date:2024-01-03
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (4.17 Å)
Cite:Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain.
Nat Commun, 15, 2024
8JY4
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Cryo-EM structure of human ABC transporter ABCC2 in apo' state
Descriptor: ATP-binding cassette sub-family C member 2
Authors:Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z.
Deposit date:2023-07-02
Release date:2024-01-03
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain.
Nat Commun, 15, 2024
8JXU
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Cryo-EM structure of human ABC transporter ABCC2 under active turnover condition
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 2, ...
Authors:Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z.
Deposit date:2023-07-01
Release date:2024-01-03
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain.
Nat Commun, 15, 2024
8JXQ
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Cryo-EM structure of bilirubin ditaurate (BDT) bound human ABC transporter ABCC2
Descriptor: 2-[3-[5-[(E)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-3-[3-oxidanylidene-3-(2-sulfoethylamino)propyl]-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoylamino]ethanesulfonic acid, ATP-binding cassette sub-family C member 2, CHOLESTEROL
Authors:Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z.
Deposit date:2023-07-01
Release date:2024-01-03
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain.
Nat Commun, 15, 2024
8JX7
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Cryo-EM structure of human ABC transporter ABCC2
Descriptor: ATP-binding cassette sub-family C member 2
Authors:Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z.
Deposit date:2023-06-30
Release date:2024-01-03
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain.
Nat Commun, 15, 2024
8JWF
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Cryo-EM structure of Plasmodium falciparum multidrug resistance protein 1 with H1 helix in complex with MFQ
Descriptor: Mefloquine, Multidrug resistance protein 1
Authors:Li, M, Si, K.
Deposit date:2023-06-29
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:The structure of Plasmodium falciparum multidrug resistance protein 1 reveals an N-terminal regulatory domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
8JWG
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Cryo-EM structure of Plasmodium falciparum multidrug resistance protein 1 without H1 helix in complex with MFQ
Descriptor: Mefloquine, Multidrug resistance protein 1
Authors:Li, M, Si, K.
Deposit date:2023-06-29
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:The structure of Plasmodium falciparum multidrug resistance protein 1 reveals an N-terminal regulatory domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
8JWI
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Cryo-EM structure of the outward-facing Plasmodium falciparum multidrug resistance protein 1
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance protein 1
Authors:Li, M, Si, K.
Deposit date:2023-06-29
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:The structure of Plasmodium falciparum multidrug resistance protein 1 reveals an N-terminal regulatory domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
8JVH
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Cryo-EM structure of Plasmodium falciparum multidrug resistance protein 1 in the apo state with H1 helix
Descriptor: Multidrug resistance protein 1
Authors:Li, M, Si, K.
Deposit date:2023-06-28
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:The structure of Plasmodium falciparum multidrug resistance protein 1 reveals an N-terminal regulatory domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
8JW4
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Cryo-EM structure of Plasmodium falciparum multidrug resistance protein 1 in the apo state without H1 helix
Descriptor: Multidrug resistance protein 1
Authors:Li, M, Si, K.
Deposit date:2023-06-28
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:The structure of Plasmodium falciparum multidrug resistance protein 1 reveals an N-terminal regulatory domain.
Proc.Natl.Acad.Sci.USA, 120, 2023

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PDB entries from 2024-04-24

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