8JWI

Cryo-EM structure of the outward-facing Plasmodium falciparum multidrug resistance protein 1

Summary for 8JWI

Entry DOI	10.2210/pdb8jwi/pdb
EMDB information	36674 36679 36681 36682 36684
Descriptor	Multidrug resistance protein 1, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION (3 entities in total)
Functional Keywords	plasmodium falciparum, multidrug resistance protein 1, abc transporter, outward-facing, transport protein
Biological source	Plasmodium falciparum (isolate 3D7)
Total number of polymer chains	1
Total formula weight	159483.80
Authors	Li, M.,Si, K. (deposition date: 2023-06-29, release date: 2023-08-30)
Primary citation	Si, K.,He, X.,Chen, L.,Zhang, A.,Guo, C.,Li, M. The structure of Plasmodium falciparum multidrug resistance protein 1 reveals an N-terminal regulatory domain. Proc.Natl.Acad.Sci.USA, 120:e2219905120-e2219905120, 2023 Cited by PubMed: 37527341 DOI: 10.1073/pnas.2219905120 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.94 Å)

Structure validation