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8JWI

Cryo-EM structure of the outward-facing Plasmodium falciparum multidrug resistance protein 1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Multidrug resistance protein 1polymer1387158420.81UniProt (Q7K6A5)
Pfam (PF00664)
Pfam (PF00005)
Plasmodium falciparum (isolate 3D7)
2B, C
(A)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.22Chemie (ATP)
3D, E
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
Sequence modifications
A: 38 - 1419 (UniProt: Q7K6A5)
PDBExternal DatabaseDetails
Gly 33-expression tag
Gly 34-expression tag
Gly 35-expression tag
Gly 36-expression tag
Ser 37-expression tag
Gln 588Glu 588conflict
Gln 1337Glu 1337conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight158420.8
Non-Polymers*Number of molecules4
Total formula weight1063.0
All*Total formula weight159483.8
*Water molecules are not included.

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PDB entries from 2025-06-11

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