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5Y6K
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BU of 5y6k by Molmil
Human serum trnasferrin bound to a fluorescent probe
Descriptor: (2S)-6-[2-(7-azido-4-methyl-2-oxidanylidene-chromen-3-yl)ethanoylamino]-2-[bis(2-hydroxy-2-oxoethyl)amino]hexanoic acid, FE (III) ION, MALONATE ION, ...
Authors:Jiang, N, Cheng, T, Wang, M, Chan, G.C.F, Jin, L, Li, H, Sun, H.
Deposit date:2017-08-12
Release date:2018-01-24
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Tracking iron-associated proteomes in pathogens by a fluorescence approach.
Metallomics, 10, 2018
3K0V
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BU of 3k0v by Molmil
Removal of sugars and sugars-like molecules from the solution by C-lobe of lactoferrin: Crystal structure of the complex of C-lobe with beta-D-glucopyranosyl-(1->4)-beta-D-galactopyranosyl-(1->4)-alpha-D-glucopyranose at 1.9 A resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ...
Authors:Mir, R, Vikram, G, Sinha, M, Singh, N, Sharma, S, Kaur, P, Singh, T.P.
Deposit date:2009-09-25
Release date:2009-10-13
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Specific interactions of C-terminal half (C-lobe) of lactoferrin protein with edible sugars: binding and structural studies with implications on diabetes.
Int.J.Biol.Macromol., 47, 2010
1LFH
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BU of 1lfh by Molmil
MOLECULAR REPLACEMENT SOLUTION OF THE STRUCTURE OF APOLACTOFERRIN, A PROTEIN DISPLAYING LARGE-SCALE CONFORMATIONAL CHANGE
Descriptor: CHLORIDE ION, LACTOFERRIN
Authors:Anderson, B.F, Baker, E.N, Norris, G.E.
Deposit date:1991-09-04
Release date:1993-10-31
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular replacement solution of the structure of apolactoferrin, a protein displaying large-scale conformational change.
Acta Crystallogr.,Sect.B, 47, 1991
4DIG
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BU of 4dig by Molmil
Crystal Structure of C-lobe of Bovine lactoferrin Complexed with N-acetylmuramyl l-alanyl d-isoglutamine at 1.8 A Resolution
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Shukla, P.K, Gautam, L, Sinha, M, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2012-01-31
Release date:2012-02-15
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of C-lobe of Bovine lactoferrin Complexed with N-acetylmuramyl l-alanyl d-isoglutamine at 1.8 A Resolution
To be Published
6XR0
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BU of 6xr0 by Molmil
Crystal Structure of Human Melanotransferrin in complex with SC57.32 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, ...
Authors:Hayashi, K, Longenecker, K.L, Vivona, S.
Deposit date:2020-07-10
Release date:2021-01-20
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.064 Å)
Cite:Complex of human Melanotransferrin and SC57.32 Fab fragment reveals novel interdomain arrangement with ferric N-lobe and open C-lobe.
Sci Rep, 11, 2021
5DYH
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BU of 5dyh by Molmil
Ti(IV) bound human serum transferrin
Descriptor: CARBONATE ION, CITRIC ACID, Serotransferrin, ...
Authors:Saxena, M, Sharma, S, Noinaj, N, Parks, T.B, Tinoco, A.D.
Deposit date:2015-09-24
Release date:2016-04-27
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.682 Å)
Cite:Unusual Synergism of Transferrin and Citrate in the Regulation of Ti(IV) Speciation, Transport, and Toxicity.
J.Am.Chem.Soc., 138, 2016
7Q1L
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BU of 7q1l by Molmil
Glycosilated Human Serum Apo-tranferrin
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Gavira, J.A, Moreno, A, Campos-Escamilla, C, Gonzalez-Ramirez, L.A, Siliqi, D.
Deposit date:2021-10-20
Release date:2022-03-16
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-ray Characterization of Conformational Changes of Human Apo- and Holo-Transferrin.
Int J Mol Sci, 22, 2021
8FEI
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BU of 8fei by Molmil
CryoEM structure of Conalbumin from chicken egg white (sigma-Cas 1391-06-6)
Descriptor: FE (III) ION, Ovotransferrin
Authors:Newton, T.P, Zimanyi, C, Kopylov, M.
Deposit date:2022-12-06
Release date:2023-02-08
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3 Å)
Cite:CryoEM structure of Conalbumin from chicken egg white (sigma-Cas 1391-06-6)
To Be Published
6JAS
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BU of 6jas by Molmil
Human serum transferrin with iron citrate bound
Descriptor: CITRIC ACID, FE (III) ION, MALONATE ION, ...
Authors:Wang, M, Wang, H, Sun, H.
Deposit date:2019-01-25
Release date:2020-01-29
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Binding of ruthenium and osmium at non-iron sites of transferrin explains their iron-independent cellular uptake
To Be Published
5CRY
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BU of 5cry by Molmil
Structure of iron-saturated C-lobe of bovine lactoferrin at pH 6.8 indicates the softening of iron coordination
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, FE (III) ION, ...
Authors:Singh, A, Rastogi, N, Singh, P.K, Tyagi, T.K, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2015-07-23
Release date:2015-10-14
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structure of iron-saturated C-lobe of bovine lactoferrin at pH 7.0 indicates the softening of iron coordination
To Be Published
4X1D
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BU of 4x1d by Molmil
Ytterbium-bound human serum transferrin
Descriptor: GLYCEROL, MALONATE ION, Serotransferrin, ...
Authors:Wang, M, Zhang, H, Sun, H.
Deposit date:2014-11-24
Release date:2015-04-08
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:"Anion clamp" allows flexible protein to impose coordination geometry on metal ions
Chem.Commun.(Camb.), 51, 2015
5H52
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BU of 5h52 by Molmil
Structure of Titanium-bound human serum transferrin
Descriptor: CITRIC ACID, MALONATE ION, Serotransferrin, ...
Authors:Curtin, J.P, Wang, M, Sun, H.
Deposit date:2016-11-04
Release date:2017-11-08
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:The role of citrate, lactate and transferrin in determining titanium release from surgical devices into human serum.
J. Biol. Inorg. Chem., 23, 2018
7FFU
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BU of 7ffu by Molmil
Osmium-bound human serum transferrin
Descriptor: FE (III) ION, MALONATE ION, OSMIUM ION, ...
Authors:Wang, M, Sun, H.
Deposit date:2021-07-23
Release date:2022-06-22
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Binding of ruthenium and osmium at non‐iron sites of transferrin accounts for their iron-independent cellular uptake.
J.Inorg.Biochem., 234, 2022
7FFM
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BU of 7ffm by Molmil
Human serum transferrin with five osmium binding sites
Descriptor: MALONATE ION, NITRILOTRIACETIC ACID, OSMIUM ION, ...
Authors:Wang, M, Sun, H.
Deposit date:2021-07-23
Release date:2022-06-22
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.06 Å)
Cite:Binding of ruthenium and osmium at non‐iron sites of transferrin accounts for their iron-independent cellular uptake.
J.Inorg.Biochem., 234, 2022
3E9X
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BU of 3e9x by Molmil
Crystal Structure of the Complex of C-lobe of Lactoferrin with Nimesulide at 2.7 A Resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-NITRO-2-PHENOXYMETHANESULFONANILIDE, CARBONATE ION, ...
Authors:Mir, R, Balaji, K, Vikram, G, Sinha, M, Singh, N, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2008-08-24
Release date:2008-09-23
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of the Complex of C-lobe of Lactoferrin with Nimesulide at 2.7 A Resolution
To be Published
9H49
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BU of 9h49 by Molmil
Crystal structure of the adduct between human serum transferrin (apo-form) and cisplatin
Descriptor: AMMONIA, CITRIC ACID, PLATINUM (II) ION, ...
Authors:Troisi, R, Galardo, F, Ferraro, G, Sica, F, Merlino, A.
Deposit date:2024-10-17
Release date:2025-01-22
Last modified:2025-01-29
Method:X-RAY DIFFRACTION (3.52 Å)
Cite:Cisplatin/Apo-Transferrin Adduct: X-ray Structure and Binding to the Transferrin Receptor 1.
Inorg.Chem., 64, 2025
9H4V
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BU of 9h4v by Molmil
Crystal structure of the adduct formed upon reaction of aurothiomalate with human serum transferrin (apo-form)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, GOLD ION, ...
Authors:Troisi, R, Galardo, F, Messori, L, Sica, F, Merlino, A.
Deposit date:2024-10-21
Release date:2025-02-12
Last modified:2025-04-09
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:The X-ray structure of the adduct formed upon reaction of aurothiomalate with apo-transferrin: gold binding sites and a unique transferrin structure along the apo/holo transition pathway
Inorg Chem Front, 12, 2025
5WTD
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BU of 5wtd by Molmil
Structure of human serum transferrin bound ruthenium at N-lobe
Descriptor: FE (III) ION, MALONATE ION, RUTHENIUM ION, ...
Authors:Sun, H, Wang, M, Lai, T.P, Zhang, H, Hao, Q.
Deposit date:2016-12-11
Release date:2017-12-20
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Binding of ruthenium and osmium at non‐iron sites of transferrin accounts for their iron-independent cellular uptake.
J.Inorg.Biochem., 234, 2022
4X1B
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BU of 4x1b by Molmil
Human serum transferrin with ferric ion bound at the C-lobe only
Descriptor: FE (III) ION, GLYCEROL, MALONATE ION, ...
Authors:Wang, M, Zhang, H, Sun, H.
Deposit date:2014-11-24
Release date:2015-04-08
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:"Anion clamp" allows flexible protein to impose coordination geometry on metal ions
Chem.Commun.(Camb.), 51, 2015
1VFD
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BU of 1vfd by Molmil
HUMAN LACTOFERRIN, N-TERMINAL LOBE MUTANT WITH ARG 121 REPLACED BY GLU (R121E)
Descriptor: CARBONATE ION, FE (III) ION, LACTOFERRIN
Authors:Faber, H.R, Day, C.L, Baker, E.N.
Deposit date:1996-10-01
Release date:1997-04-21
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mutation of arginine 121 in lactoferrin destabilizes iron binding by disruption of anion binding: crystal structures of R121S and R121E mutants.
Biochemistry, 35, 1996
6UJ6
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BU of 6uj6 by Molmil
X-ray Crystal Structure of Chromium-transferrin with Synergistic Anion Malonate
Descriptor: BICARBONATE ION, CHROMIUM ION, GLYCEROL, ...
Authors:Petersen, C.M, Edwards, K.C, Gilbert, N.C, Vincent, J.B, Thompson, M.K.
Deposit date:2019-10-02
Release date:2020-09-30
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:X-ray structure of chromium(III)-containing transferrin: First structure of a physiological Cr(III)-binding protein.
J.Inorg.Biochem., 210, 2020
1VFE
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BU of 1vfe by Molmil
HUMAN LACTOFERRIN, N-TERMINAL LOBE MUTANT WITH ARG 121 REPLACED BY SER (R121S)
Descriptor: CARBONATE ION, FE (III) ION, HUMAN LACTOFERRIN
Authors:Faber, H.R, Day, C.L, Baker, E.N.
Deposit date:1996-10-01
Release date:1997-04-01
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mutation of arginine 121 in lactoferrin destabilizes iron binding by disruption of anion binding: crystal structures of R121S and R121E mutants.
Biochemistry, 35, 1996
3FGS
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BU of 3fgs by Molmil
Crystal structure of G65R/K206E double mutant of the N-lobe human transferrin
Descriptor: CARBONATE ION, FE (III) ION, Serotransferrin
Authors:Halbrooks, P.J, Mason, A.B, Everse, S.J.
Deposit date:2008-12-08
Release date:2009-05-19
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Functional Consequences of the Substitution of Glycine 65 with Arginine in the N-Lobe of Human Transferrin.
Biochemistry, 48, 2009
6WB6
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BU of 6wb6 by Molmil
2.05 A resolution structure of transferrin 1 from Manduca sexta
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ...
Authors:Lovell, S, Kashipathy, M.M, Battaile, K.P, Weber, J.J, Gorman, M.J.
Deposit date:2020-03-26
Release date:2020-11-25
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural insight into the novel iron-coordination and domain interactions of transferrin-1 from a model insect, Manduca sexta.
Protein Sci., 30, 2021
5HBC
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BU of 5hbc by Molmil
Intermediate structure of iron-saturated C-lobe of bovine lactoferrin at 2.79 Angstrom resolution indicates the softening of iron coordination
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, FE (III) ION, ...
Authors:Singh, A, Rastogi, N, Singh, P.K, Tyagi, T.K, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2015-12-31
Release date:2016-01-20
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structure of iron saturated C-lobe of bovine lactoferrin at pH 6.8 indicates a weakening of iron coordination
Proteins, 84, 2016

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