10MH
  • Download 10mh
  • View 10mh
Molmil generated image of 10mh
TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH ADOHCY AND HEMIMETHYLATED DNA CONTAINING 5,6-DIHYDRO-5-AZACYTOSINE AT THE TARGET
Descriptor:CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI/DNA COMPLEX
Authors:Sheikhnejad, G., Brank, A., Christman, J.K., Goddard, A., Alvarez, E., Ford Junior, H., Marquez, V.E., Marasco, C.J., Sufrin, J.R., O'Gara, M., Cheng, X.
Deposit date:1998-08-10
Release date:1999-02-09
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Mechanism of inhibition of DNA (cytosine C5)-methyltransferases by oligodeoxyribonucleotides containing 5,6-dihydro-5-azacytosine.
J.Mol.Biol., 285, 1999
1DCT
  • Download 1dct
  • View 1dct
Molmil generated image of 1dct
DNA (CYTOSINE-5) METHYLASE FROM HAEIII COVALENTLY BOUND TO DNA
Descriptor:MODIFICATION METHYLASE HAEIII (E.C.2.1.1.73)/DNA COMPLEX
Authors:Reinisch, K.M., Chen, L., Verdine, G.L., Lipscomb, W.N.
Deposit date:1995-05-17
Release date:1995-09-15
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of HaeIII methyltransferase convalently complexed to DNA: an extrahelical cytosine and rearranged base pairing.
Cell(Cambridge,Mass.), 82, 1995
1FJX
  • Download 1fjx
  • View 1fjx
Molmil generated image of 1fjx
STRUCTURE OF TERNARY COMPLEX OF HHAI METHYLTRANSFERASE MUTANT (T250G) IN COMPLEX WITH DNA AND ADOHCY
Descriptor:HHAI METHYLTRANSFERASE MUTANT (T250G) (E.C. 2.1.1.73), DNA AND ADOHCY
Authors:Vilkaitis, G., Dong, A., Weinhold, E., Cheng, X., Klimasauskas, S.
Deposit date:2000-08-08
Release date:2000-12-15
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Functional roles of the conserved threonine 250 in the target recognition domain of HhaI DNA methyltransferase.
J.Biol.Chem., 275, 2000
1HMY
  • Download 1hmy
  • View 1hmy
Molmil generated image of 1hmy
CRYSTAL STRUCTURE OF THE HHAI DNA METHYLTRANSFERASE COMPLEXED WITH S-ADENOSYL-L-METHIONINE
Descriptor:HHAI DNA (CYTOSINE-C5-)-METHYLTRANSFERASE (E.C.2.1.1.37) COMPLEX WITH S-ADENOSYL-L-METHIONINE
Authors:Cheng, X.
Deposit date:1993-08-05
Release date:1993-10-31
Last modified:2012-02-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the HhaI DNA methyltransferase complexed with S-adenosyl-L-methionine.
Cell(Cambridge,Mass.), 74, 1993
1M0E
  • Download 1m0e
  • View 1m0e
Molmil generated image of 1m0e
ZEBULARINE: A NOVEL DNA METHYLATION INHIBITOR THAT FORMS A COVALENT COMPLEX WITH DNA METHYLTRANSFERASE
Descriptor:Modification methylase HhaI/DNA Complex
Authors:Zhou, L., Cheng, X., Connolly, B.A., Dickman, M.J., Hurd, P.J., Hornby, D.P.
Deposit date:2002-06-12
Release date:2002-09-18
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:ZEBULARINE: A NOVEL DNA METHYLATION INHIBITOR THAT FORMS A COVALENT COMPLEX WITH DNA METHYLTRANSFERASES
J.MOL.BIOL., 321, 2002
1MHT
  • Download 1mht
  • View 1mht
Molmil generated image of 1mht
COVALENT TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE, DNA AND S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:HHAI METHYLTRANSFERASE (E.C.2.1.1.73)/DNA COMPLEX + S-ADENOSYL-L- HOMOSYTEINE
Authors:Cheng, X.
Deposit date:1994-12-08
Release date:1995-06-03
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:HhaI methyltransferase flips its target base out of the DNA helix.
Cell(Cambridge,Mass.), 76, 1994
1SKM
  • Download 1skm
  • View 1skm
Molmil generated image of 1skm
HHAI METHYLTRANSFERASE IN COMPLEX WITH DNA CONTAINING AN ABASIC SOUTH CARBOCYCLIC SUGAR AT ITS TARGET SITE
Descriptor:Modification methylase HhaI /5'-D(*TP*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3' /5'-D(*T*GP*TP*CP*AP*GP*(HCX)P*GP*CP*AP*TP*GP*G)-3'
Authors:Horton, J.R., Ratner, G., Banavali, N., Huang, N., Marquez, V.E., MacKerell, A.D., Cheng, X.
Deposit date:2004-03-05
Release date:2004-08-24
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Caught in the act: visualization of an intermediate in the DNA base-flipping pathway induced by HhaI methyltransferase
Nucleic Acids Res., 32, 2004
1SVU
  • Download 1svu
  • View 1svu
Molmil generated image of 1svu
STRUCTURE OF THE Q237W MUTANT OF HHAI DNA METHYLTRANSFERASE: AN INSIGHT INTO PROTEIN-PROTEIN INTERACTIONS
Descriptor:Modification methylase HhaI (E.C.2.1.1.37)
Authors:Dong, A., Zhou, L., Zhang, X., Stickel, S., Roberts, R.J., Cheng, X.
Deposit date:2004-03-30
Release date:2004-06-29
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Structure of the Q237W mutant of HhaI DNA methyltransferase: an insight into protein-protein interactions
Biol.Chem., 385, 2004
2HMY
  • Download 2hmy
  • View 2hmy
Molmil generated image of 2hmy
BINARY COMPLEX OF HHAI METHYLTRANSFERASE WITH ADOMET FORMED IN THE PRESENCE OF A SHORT NONPSECIFIC DNA OLIGONUCLEOTIDE
Descriptor:CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI
Authors:O'Gara, M., Zhang, X., Roberts, R.J., Cheng, X.
Deposit date:1999-02-08
Release date:1999-03-19
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structure of a binary complex of HhaI methyltransferase with S-adenosyl-L-methionine formed in the presence of a short non-specific DNA oligonucleotide.
J.Mol.Biol., 287, 1999
2HR1
  • Download 2hr1
  • View 2hr1
Molmil generated image of 2hr1
TERNARY STRUCTURE OF WT M.HHAI C5-CYTOSINE DNA METHYLTRANSFERASE WITH UNMODIFIED DNA AND ADOHCY
Descriptor:Transferase/DNA Complex
Authors:Shieh, F.
Deposit date:2006-07-19
Release date:2006-09-19
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:The Role of Arg165 Towards Base Flipping, Base Stabilization and Catalysis in M.HhaI.
J.Mol.Biol., 362, 2006
2I9K
  • Download 2i9k
  • View 2i9k
Molmil generated image of 2i9k
ENGINEERED EXTRAHELICAL BASE DESTABILIZATION ENHANCES SEQUENCE DISCRIMINATION OF DNA METHYLTRANSFERASE M.HHAI
Descriptor:Modification methylase HhaI/DNA Complex, S-Adenosyl-L-Homocysteine
Authors:Youngblood, B., Shieh, F.K., De Los Rios, S., Perona, J.J., Reich, N.O.
Deposit date:2006-09-05
Release date:2006-10-10
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Engineered Extrahelical Base Destabilization Enhances Sequence Discrimination of DNA Methyltransferase M.HhaI
J.Mol.Biol., 362, 2006
2Z6A
  • Download 2z6a
  • View 2z6a
Molmil generated image of 2z6a
S-ADENOSYL-L-METHIONINE-DEPENDENT METHYL TRANSFER: OBSERVABLE PRECATALYTIC INTERMEDIATES DURING DNA CYTOSINE METHYLATION
Descriptor:Transferase(E.C.2.1.1.37)/DNA Complex
Authors:Shieh, F.K.
Deposit date:2007-07-25
Release date:2007-08-21
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:S-Adenosyl-l-methionine-Dependent Methyl Transfer: Observable Precatalytic Intermediates during DNA Cytosine Methylation
Biochemistry, 46, 2007
2Z6Q
  • Download 2z6q
  • View 2z6q
Molmil generated image of 2z6q
TERNARY STRUCTURE OF ARG165ALA M.HHAI C5-CYTOSINE DNA METHYLTRANSFERASE WITH UNMODIFIED DNA AND ADOHCY
Descriptor:Modification methylase HhaI(E.C.2.1.1.37)/DNA Complex
Authors:Shieh, F.K.
Deposit date:2007-08-08
Release date:2007-08-28
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:The role of Arg165 towards base flipping, base stabilization and catalysis in M.HhaI
J.Mol.Biol., 362, 2006
2Z6U
  • Download 2z6u
  • View 2z6u
Molmil generated image of 2z6u
TERNARY STRUCTURE OF THE GLU119ALA M.HHAI, C5-CYTOSINE DNA METHYLTRANSFERASE, WITH UNMODIFIED DNA AND ADOHCY
Descriptor:Transferase(E.C.2.1.1.37)/DNA Complex
Authors:Shieh, F.K.
Deposit date:2007-08-09
Release date:2007-11-20
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:AdoMet-dependent Methyl-transfer: Glu(119) Is Essential for DNA C5-Cytosine Methyltransferase M.HhaI
J.Mol.Biol., 373, 2007
2ZCJ
  • Download 2zcj
  • View 2zcj
Molmil generated image of 2zcj
TERNARY STRUCTURE OF THE GLU119GLN M.HHAI, C5-CYTOSINE DNA METHYLTRANSFERASE, WITH UNMODIFIED DNA AND ADOHCY
Descriptor:Modification methylase HhaI(E.C.2.1.1.37)/DNA Complex
Authors:Shieh, F.K., Reich, N.O.
Deposit date:2007-11-09
Release date:2007-12-04
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:AdoMet-dependent Methyl-transfer: Glu(119) Is Essential for DNA C5-Cytosine Methyltransferase M.HhaI
J.Mol.Biol., 373, 2007
3EEO
  • Download 3eeo
  • View 3eeo
Molmil generated image of 3eeo
M. HHAI CO-CRYSTALLIZED WITH SYNTHETIC DSDNA CONTAINING A PROPANE DIOL IN PLACE OF THE DEOXYCYTIDINE RESIDUE TARGETED FOR METHYLATION.
Descriptor:Modification methylase HhaI (E.C.2.1.1.37)/DNA Complex
Authors:Porta, J.C., Christman, J.K., Borgstahl, G.E.O.
Deposit date:2008-09-05
Release date:2010-03-02
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:M. HhaI co-crystallized with synthetic dsDNA containing a propane diol in place of the deoxycytidine residue targeted for methylation.
To be Published
3MHT
  • Download 3mht
  • View 3mht
Molmil generated image of 3mht
TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH UNMODIFIED DNA AND ADOHCY
Descriptor:URACIL-DNA GLYCOSYLASE (E.C.2.1.1.73)/DNA COMPLEX + S-ADENOSYL-L-HOMOCYSTEINE
Authors:O'Gara, M., Klimasauskas, S., Roberts, R.J., Cheng, X.
Deposit date:1996-07-24
Release date:1997-01-27
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Enzymatic C5-cytosine methylation of DNA: mechanistic implications of new crystal structures for HhaL methyltransferase-DNA-AdoHcy complexes.
J.Mol.Biol., 261, 1996
3QV2
  • Download 3qv2
  • View 3qv2
Molmil generated image of 3qv2
STRUCTURE ANALYSIS OF ENTAMOEBA HISTOLYTICA METHYLTRANSFERASE EHMETH
Descriptor:5-cytosine DNA methyltransferase (E.C.2.1.1.37)
Authors:Schulz, E.C., Roth, H.M., Ankri, S., Ficner, R.
Deposit date:2011-02-25
Release date:2012-04-11
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structure Analysis of Entamoeba histolytica Methyltransferase
To be Published
4DKJ
  • Download 4dkj
  • View 4dkj
Molmil generated image of 4dkj
CPG SPECIFIC METHYLTRANSFERASE IN COMPLEX WITH TARGET DNA
Descriptor:Cytosine-specific methyltransferase (E.C.2.1.1.37)
Authors:Wojciechowski, M., Czapinska, H., Bochtler, M.
Deposit date:2012-02-03
Release date:2012-12-05
Last modified:2013-01-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:CpG underrepresentation and the bacterial CpG-specific DNA methyltransferase M.MpeI.
Proc.Natl.Acad.Sci.USA, 110, 2013
4H0N
  • Download 4h0n
  • View 4h0n
Molmil generated image of 4h0n
CRYSTAL STRUCTURE OF SPODOPTERA FRUGIPERDA DNMT2 E260A/E261A/K263A MUTANT
Descriptor:DNMT2 (E.C.2.1.1.-)
Authors:Li, S., Du, J., Yang, H., Yin, J., Zhong, J., Ding, J.
Deposit date:2012-09-09
Release date:2012-11-14
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (2.712 Å)
Cite:Functional and structural characterization of DNMT2 from Spodoptera frugiperda.
J Mol Cell Biol, 5, 2013
4MHT
  • Download 4mht
  • View 4mht
Molmil generated image of 4mht
TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH NATIVE DNA AND ADOHCY
Descriptor:HHAI METHYLTRANSFERASE (E.C.2.1.1.73)/DNA COMPLEX + S-ADENOSYL-L-HOMOSYTEINE
Authors:Cheng, X.
Deposit date:1996-07-24
Release date:1997-01-27
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Enzymatic C5-cytosine methylation of DNA: mechanistic implications of new crystal structures for HhaL methyltransferase-DNA-AdoHcy complexes.
J.Mol.Biol., 261, 1996
4ONJ
  • Download 4onj
  • View 4onj
Molmil generated image of 4onj
CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF NTDRM
Descriptor:DNA methyltransferase (E.C.2.1.1.-)
Authors:Du, J., Patel, D.J.
Deposit date:2014-01-28
Release date:2014-06-04
Method:X-RAY DIFFRACTION (2.807 Å)
Cite:Molecular Mechanism of Action of Plant DRM De Novo DNA Methyltransferases.
Cell(Cambridge,Mass.), 157, 2014
4ONQ
  • Download 4onq
  • View 4onq
Molmil generated image of 4onq
CRYSTAL STRUCTURE OF NTDRM E283S/R309S/F310S/Y590S/D591S MUTANT
Descriptor:DNA methyltransferase (E.C.2.1.1.-)
Authors:Du, J., Patel, D.J.
Deposit date:2014-01-28
Release date:2014-06-04
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Molecular Mechanism of Action of Plant DRM De Novo DNA Methyltransferases.
Cell(Cambridge,Mass.), 157, 2014
5CIY
  • Download 5ciy
  • View 5ciy
Molmil generated image of 5ciy
STRUCTURAL BASIS OF THE RECOGNITION OF H3K36ME3 BY DNMT3B PWWP DOMAIN
Descriptor:Modification methylase HhaI/DNA Complex
Authors:RONDELET, G., DAL MASO, T., WILLEMS, L., WOUTERS, J.
Deposit date:2015-07-13
Release date:2016-03-30
Last modified:2016-05-04
Method:X-RAY DIFFRACTION (1.594 Å)
Cite:Structural basis for recognition of histone H3K36me3 nucleosome by human de novo DNA methyltransferases 3A and 3B.
J.Struct.Biol., 194, 2016
5MHT
  • Download 5mht
  • View 5mht
Molmil generated image of 5mht
TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH HEMIMETHYLATED DNA AND ADOHCY
Descriptor:HHAI METHYLTRANSFERASE (E.C.2.1.1.7)/DNA COMPLEX + S-ADENOSYL-L-HOMOCYSTEINE
Authors:Cheng, X.
Deposit date:1996-10-22
Release date:1997-07-23
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A structural basis for the preferential binding of hemimethylated DNA by HhaI DNA methyltransferase.
J.Mol.Biol., 263, 1996
<123>
PDBj@FacebookPDBj@TwitterwwPDBwwPDB FoundationEM DataBank

Copyright © 2013-2017 Protein Data Bank Japan