Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7F0R
DownloadVisualize
BU of 7f0r by Molmil
Cryo-EM structure of Pseudomonas aeruginosa SutA transcription activation complex
Descriptor: DNA (70-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:He, D.W, You, L.L, Zhang, Y.
Deposit date:2021-06-06
Release date:2022-07-27
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding.
Nat Commun, 13, 2022
7XL4
DownloadVisualize
BU of 7xl4 by Molmil
Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes with transcription factor SutA (closed lobe)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:He, D.W, You, L.L, Zhang, Y.
Deposit date:2022-04-21
Release date:2022-07-27
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding.
Nat Commun, 13, 2022
7XL3
DownloadVisualize
BU of 7xl3 by Molmil
Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes with transcription factor SutA (open lobe)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:He, D.W, You, L.L, Zhang, Y.
Deposit date:2022-04-21
Release date:2022-07-27
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding.
Nat Commun, 13, 2022
7VF9
DownloadVisualize
BU of 7vf9 by Molmil
Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:He, D.W, You, L.L, Zhang, Y.
Deposit date:2021-09-10
Release date:2022-07-27
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (4.04 Å)
Cite:Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding.
Nat Commun, 13, 2022
7XYA
DownloadVisualize
BU of 7xya by Molmil
The cryo-EM structure of an AlpA-loading complex
Descriptor: AlpA, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Wen, A, Feng, Y.
Deposit date:2022-06-01
Release date:2022-07-20
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of AlpA-dependent transcription antitermination.
Nucleic Acids Res., 50, 2022
7SZK
DownloadVisualize
BU of 7szk by Molmil
Cryo-EM structure of 27a bound to E. coli RNAP and rrnBP1 promoter complex
Descriptor: (2S,7R,7aR,13aP,16Z,18E,20S,21S,22R,23R,24R,25S,26R,27S,28E)-5,21,23-trihydroxy-27-methoxy-2,4,16,20,22,24,26-heptamethyl-10-[4-(2-methylpropyl)piperazin-1-yl]-12-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)-1,6,15-trioxo-1,2,7,7a-tetrahydro-6H-2,7-(epoxypentadeca[1,11,13]trienoimino)[1]benzofuro[4,5-a]phenoxazin-25-yl acetate, DNA (5'-D(P*CP*TP*CP*GP*TP*AP*GP*AP*GP*TP*CP*CP*GP*TP*GP*TP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Shin, Y, Murakami, K.S.
Deposit date:2021-11-28
Release date:2022-07-13
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Optimization of Benzoxazinorifamycins to Improve Mycobacterium tuberculosis RNA Polymerase Inhibition and Treatment of Tuberculosis.
Acs Infect Dis., 8, 2022
7SZJ
DownloadVisualize
BU of 7szj by Molmil
Cryo-EM structure of Rifamycin bound to E. coli RNAP and rrnBP1 promoter complex
Descriptor: DNA (49-MER), DNA (57-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Shin, Y, Murakami, K.S.
Deposit date:2021-11-28
Release date:2022-07-13
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:Optimization of Benzoxazinorifamycins to Improve Mycobacterium tuberculosis RNA Polymerase Inhibition and Treatment of Tuberculosis.
Acs Infect Dis., 8, 2022
7N4E
DownloadVisualize
BU of 7n4e by Molmil
Escherichia coli sigma 70-dependent paused transcription elongation complex
Descriptor: 5'-R(*UP*UP*CP*GP*GP*AP*GP*AP*GP*GP*UP*A)-3', DNA (61-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Molodtsov, V, Su, M, Ebright, R.H.
Deposit date:2021-06-04
Release date:2022-06-15
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural and mechanistic basis of sigma-dependent transcriptional pausing.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VWZ
DownloadVisualize
BU of 7vwz by Molmil
Cryo-EM structure of Rob-dependent transcription activation complex in a unique conformation
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W, Feng, Y, Shi, J.
Deposit date:2021-11-12
Release date:2022-06-08
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of transcription activation by Rob, a pleiotropic AraC/XylS family regulator.
Nucleic Acids Res., 50, 2022
7VWY
DownloadVisualize
BU of 7vwy by Molmil
Cryo-EM structure of Rob-dependent transcription activation complex in a unique conformation
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W, Feng, Y.
Deposit date:2021-11-12
Release date:2022-06-08
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4.57 Å)
Cite:Structural basis of transcription activation by Rob, a pleiotropic AraC/XylS family regulator.
Nucleic Acids Res., 50, 2022
7RWI
DownloadVisualize
BU of 7rwi by Molmil
Mycobacterium tuberculosis RNA polymerase sigma L holoenzyme open promoter complex containing TNP-2198
Descriptor: (3aM,9S,10bP,14S,15R,16S,17R,18R,19R,20S,21S,25R)-6,18,20-trihydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-[2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl]-5,10,26-trioxo-3,5,9,10-tetrahydrospiro[9,4-(epoxypentadecanoimino)furo[2',3':7,8]naphtho[1,2-d]imidazole-2,4'-piperidin]-16-yl acetate, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Molodtsov, V, Ebright, R.H.
Deposit date:2021-08-19
Release date:2022-03-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens.
J.Med.Chem., 65, 2022
7MLB
DownloadVisualize
BU of 7mlb by Molmil
Crystal structure of Thermus thermophilus transcription initiation complex with 5nt RNA
Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*AP*GP*GP*GP*AP*TP*GP*CP*AP*G)-3'), DNA (5'-D(P*CP*TP*GP*CP*AP*TP*CP*CP*CP*TP*GP*AP*GP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Liu, Y, Ebright, R.H.
Deposit date:2021-04-28
Release date:2022-02-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural and mechanistic basis of reiterative transcription initiation.
Proc.Natl.Acad.Sci.USA, 119, 2022
7MLI
DownloadVisualize
BU of 7mli by Molmil
Crystal structure of Thermus thermophilus reiterative transcription complex with 5nt oligo-C RNA
Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*CP*TP*AP*CP*GP*GP*AP*TP*G)-3'), DNA (5'-D(P*CP*AP*TP*CP*CP*GP*TP*AP*GP*GP*GP*CP*GP*GP*G)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Liu, Y, Ebright, R.H.
Deposit date:2021-04-28
Release date:2022-02-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural and mechanistic basis of reiterative transcription initiation.
Proc.Natl.Acad.Sci.USA, 119, 2022
7MLJ
DownloadVisualize
BU of 7mlj by Molmil
Crystal structure of Thermus thermophilus reiterative transcription complex with 4nt oligo-G RNA
Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*GP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA (5'-D(P*CP*AP*TP*CP*CP*GP*TP*GP*CP*CP*CP*TP*GP*AP*G)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Liu, Y, Ebright, R.H.
Deposit date:2021-04-28
Release date:2022-02-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.75 Å)
Cite:Structural and mechanistic basis of reiterative transcription initiation.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RDQ
DownloadVisualize
BU of 7rdq by Molmil
Cryo-EM structure of Thermus thermophilus reiterative transcription complex with 11nt oligo-G RNA
Descriptor: DNA (31-MER) nontemplate strand, DNA (31-MER) template strand, DNA-directed RNA polymerase subunit alpha, ...
Authors:Liu, Y, Ebright, R.H.
Deposit date:2021-07-10
Release date:2022-02-02
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural and mechanistic basis of reiterative transcription initiation.
Proc.Natl.Acad.Sci.USA, 119, 2022
7L7B
DownloadVisualize
BU of 7l7b by Molmil
Clostridioides difficile RNAP with fidaxomicin
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Boyaci, H, Campbell, E.A, Darst, S.A, Chen, J.
Deposit date:2020-12-28
Release date:2022-02-02
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Basis of narrow-spectrum activity of fidaxomicin on Clostridioides difficile.
Nature, 604, 2022
7P5X
DownloadVisualize
BU of 7p5x by Molmil
Mycobacterial RNAP with transcriptional activator PafBC
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Mueller, A.U, Kummer, E, Schilling, C.M, Ban, N, Weber-Ban, E.
Deposit date:2021-07-15
Release date:2021-12-22
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Transcriptional control of mycobacterial DNA damage response by sigma adaptation.
Sci Adv, 7, 2021
7BEG
DownloadVisualize
BU of 7beg by Molmil
Structures of class I bacterial transcription complexes
Descriptor: Class I pacrA promoter non-template DNA, Class I pacrA promoter template DNA, DNA-directed RNA polymerase subunit alpha, ...
Authors:Ye, F.Z, Hao, M, Zhang, X.D.
Deposit date:2020-12-23
Release date:2021-12-01
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structures of Class I and Class II Transcription Complexes Reveal the Molecular Basis of RamA-Dependent Transcription Activation.
Adv Sci, 9, 2022
7BEF
DownloadVisualize
BU of 7bef by Molmil
Structures of class II bacterial transcription complexes
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Hao, M, Ye, F.Z, Zhang, X.D.
Deposit date:2020-12-23
Release date:2021-12-01
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structures of Class I and Class II Transcription Complexes Reveal the Molecular Basis of RamA-Dependent Transcription Activation.
Adv Sci, 9, 2022
7DY6
DownloadVisualize
BU of 7dy6 by Molmil
A refined cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo) with SspA
Descriptor: DNA (63-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Lin, W.
Deposit date:2021-01-20
Release date:2021-11-17
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:A unique binding between SspA and RNAP beta' NTH across low-GC Gram-negative bacteria facilitates SspA-mediated transcription regulation.
Biochem.Biophys.Res.Commun., 583, 2021
7F75
DownloadVisualize
BU of 7f75 by Molmil
Cryo-EM structure of Spx-dependent transcription activation complex
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W, Feng, Y, Shi, J.
Deposit date:2021-06-28
Release date:2021-10-13
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis of transcription activation by the global regulator Spx.
Nucleic Acids Res., 49, 2021
7MKE
DownloadVisualize
BU of 7mke by Molmil
Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 2)
Descriptor: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Saecker, R.M, Darst, S.A, Chen, J.
Deposit date:2021-04-23
Release date:2021-09-29
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
Proc.Natl.Acad.Sci.USA, 118, 2021
7MKJ
DownloadVisualize
BU of 7mkj by Molmil
Cryo-EM structure of Escherichia coli RNA polymerase bound to T7A1 promoter DNA
Descriptor: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Saecker, R.M, Darst, S.A, Chen, J.
Deposit date:2021-04-23
Release date:2021-09-29
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
Proc.Natl.Acad.Sci.USA, 118, 2021
7MKI
DownloadVisualize
BU of 7mki by Molmil
Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR (-5G to C) promoter DNA
Descriptor: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Saecker, R.M, Darst, S.A, Chen, J.
Deposit date:2021-04-23
Release date:2021-09-29
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
Proc.Natl.Acad.Sci.USA, 118, 2021
7MKD
DownloadVisualize
BU of 7mkd by Molmil
Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 1)
Descriptor: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Saecker, R.M, Darst, S.A, Chen, J.
Deposit date:2021-04-23
Release date:2021-09-29
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
Proc.Natl.Acad.Sci.USA, 118, 2021

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon