2V88
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CRYSTAL STRUCTURE OF RAG2-PHD FINGER IN COMPLEX WITH H3R2ME2SK4ME2 PEPTIDE
Descriptor:VDJ RECOMBINATION-ACTIVATING PROTEIN 2, H3R2ME2SK4ME3 PEPTIDE, ZINC ION
Authors:Ramon-Maiques, S., Yang, W.
Deposit date:2007-08-03
Release date:2007-12-11
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Plant Homeodomain Finger of Rag2 Recognizes Histone H3 Methylated at Both Lysine-4 and Arginine-2.
Proc.Natl.Acad.Sci.USA, 104, 2007
3KV4
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STRUCTURE OF PHF8 IN COMPLEX WITH HISTONE H3
Descriptor:PHD finger protein 8, Histone H3-like, ZINC ION, ...
Authors:Horton, J.R., Upadhyay, A.K., Qi, H.H., Zhang, X., Shi, Y., Cheng, X.
Deposit date:2009-11-29
Release date:2009-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.
Nat.Struct.Mol.Biol., 17, 2010
3KV5
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STRUCTURE OF KIAA1718, HUMAN JUMONJI DEMETHYLASE, IN COMPLEX WITH N-OXALYLGLYCINE
Descriptor:JmjC domain-containing histone demethylation protein 1D, ZINC ION, FE (II) ION, ...
Authors:Horton, J.R., Upadhyay, A.K., Qi, H.H., Zhang, X., Shi, Y., Cheng, X.
Deposit date:2009-11-29
Release date:2009-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.
Nat.Struct.Mol.Biol., 17, 2010
3KV6
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STRUCTURE OF KIAA1718, HUMAN JUMONJI DEMETHYLASE, IN COMPLEX WITH ALPHA-KETOGLUTARATE
Descriptor:JmjC domain-containing histone demethylation protein 1D, ZINC ION, FE (II) ION, ...
Authors:Horton, J.R., Upadhyay, A.K., Qi, H.H., Zhang, X., Shi, Y., Cheng, X.
Deposit date:2009-11-29
Release date:2009-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.
Nat.Struct.Mol.Biol., 17, 2010
3KV9
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STRUCTURE OF KIAA1718 JUMONJI DOMAIN
Descriptor:JmjC domain-containing histone demethylation protein 1D, FE (II) ION, OXYGEN MOLECULE
Authors:Horton, J.R., Upadhyay, A.K., Qi, H.H., Zhang, X., Shi, Y., Cheng, X.
Deposit date:2009-11-29
Release date:2009-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.
Nat.Struct.Mol.Biol., 17, 2010
3KVA
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STRUCTURE OF KIAA1718 JUMONJI DOMAIN IN COMPLEX WITH ALPHA-KETOGLUTARATE
Descriptor:JmjC domain-containing histone demethylation protein 1D, FE (II) ION, OXYGEN MOLECULE, ...
Authors:Horton, J.R., Upadhyay, A.K., Qi, H.H., Zhang, X., Shi, Y., Cheng, X.
Deposit date:2009-11-29
Release date:2009-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.
Nat.Struct.Mol.Biol., 17, 2010
3KVB
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STRUCTURE OF KIAA1718 JUMONJI DOMAIN IN COMPLEX WITH N-OXALYLGLYCINE
Descriptor:JmjC domain-containing histone demethylation protein 1D, NICKEL (II) ION, OXYGEN MOLECULE, ...
Authors:Horton, J.R., Upadhyay, A.K., Qi, H.H., Zhang, X., Shi, Y., Cheng, X.
Deposit date:2009-11-29
Release date:2009-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.
Nat.Struct.Mol.Biol., 17, 2010
4AFL
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THE CRYSTAL STRUCTURE OF THE ING4 DIMERIZATION DOMAIN REVEALS THE FUNCTIONAL ORGANIZATION OF THE ING FAMILY OF CHROMATIN BINDING PROTEINS.
Descriptor:INHIBITOR OF GROWTH PROTEIN 4
Authors:Culurgioni, S., Munoz, I.G., Moreno, A., Palacios, A., Villate, M., Palmero, I., Montoya, G., Blanco, F.J.
Deposit date:2012-01-19
Release date:2012-02-22
Last modified:2012-07-11
Method:X-RAY DIFFRACTION (2.275 Å)
Cite:Crystal Structure of Inhibitor of Growth 4 (Ing4) Dimerization Domain Reveals Functional Organization of Ing Family of Chromatin-Binding Proteins.
J.Biol.Chem., 287, 2012
2GF7
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DOUBLE TUDOR DOMAIN STRUCTURE
Descriptor:Jumonji domain-containing protein 2A, SULFATE ION
Authors:Huang, Y., Fang, J., Bedford, M.T., Zhang, Y., Xu, R.M.
Deposit date:2006-03-21
Release date:2006-05-02
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A
Science, 312, 2006
2GFA
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DOUBLE TUDOR DOMAIN COMPLEX STRUCTURE
Descriptor:Jumonji domain-containing protein 2A, peptide
Authors:Huang, Y., Fang, J., Bedford, M.T., Zhang, Y., Xu, R.M.
Deposit date:2006-03-21
Release date:2006-05-02
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A
Science, 312, 2006
2GP3
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CRYSTAL STRUCTURE OF THE CATALYTIC CORE DOMAIN OF JMJD2A
Descriptor:Jumonji domain-containing protein 2A, ZINC ION, FE (II) ION
Authors:Chen, Z., Zang, J., Whetstine, J., Hong, X., Davrazou, F., Kutateladze, T.G., Simpson, M., Dai, S., Hagman, J., Shi, Y., Zhang, G.
Deposit date:2006-04-16
Release date:2006-05-23
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural insights into histone demethylation by JMJD2 family members
Cell(Cambridge,Mass.), 125, 2006
2GP5
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CRYSTAL STRUCTURE OF CATALYTIC CORE DOMAIN OF JMJD2A COMPLEXED WITH ALPHA-KETOGLUTARATE
Descriptor:Jumonji domain-containing protein 2A, ZINC ION, FE (II) ION, ...
Authors:Chen, Z., Zang, J., Whetstine, J., Hong, X., Davrazou, F., Kutateladze, T.G., Simpson, M., Dai, S., Hagman, J., Shi, Y., Zhang, G.
Deposit date:2006-04-16
Release date:2006-05-23
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural insights into histone demethylation by JMJD2 family members
Cell(Cambridge,Mass.), 125, 2006
2JMJ
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NMR SOLUTION STRUCTURE OF THE PHD DOMAIN FROM THE YEAST YNG1 PROTEIN IN COMPLEX WITH H3(1-9)K4ME3 PEPTIDE
Descriptor:Protein YNG1, Histone H3, ZINC ION
Authors:Ilin, S., Taverna, S.D., Rogers, R.S., Tanny, J.C., Lavender, H., Li, H., Baker, L., Boyle, J., Blair, L.P., Chait, B.T., Patel, D.J., Aitchison, J.D., Tackett, A.J., Allis, C.D.
Deposit date:2006-11-15
Release date:2007-07-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs
Mol.Cell, 24, 2006
2M1R
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PHD DOMAIN OF ING4 N214D MUTANT
Descriptor:Inhibitor of growth protein 4, ZINC ION
Authors:Blanco, F.J.
Deposit date:2012-12-05
Release date:2012-12-26
Method:SOLUTION NMR
Cite:Functional impact of cancer-associated mutations in the tumor suppressor protein ING4.
Carcinogenesis, 31, 2010
2MUM
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SOLUTION STRUCTURE OF THE PHD DOMAIN OF YEAST YNG2
Descriptor:Chromatin modification-related protein YNG2, ZINC ION
Authors:Taeb, S., Kaustov, L., Lemak, A., Farhadi, S., Sheng, Y.
Deposit date:2014-09-12
Release date:2014-12-24
Method:SOLUTION NMR
Cite:Solution structure of the PHD domain of Yeast YNG2
To be Published
2OQ6
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CRYSTAL STRUCTURE OF JMJD2A COMPLEXED WITH HISTONE H3 PEPTIDE TRIMETHYLATED AT LYS9
Descriptor:JmjC domain-containing histone demethylation protein 3A, synthetic peptide, NICKEL (II) ION, ...
Authors:Pilka, E.S., Ng, S.S., Kavanagh, K.L., McDonough, M.A., Savitsky, P., von Delft, F., Arrowsmith, C.H., Weigelt, J., Edwards, A., Sundstrom, M., Schofield, C.J., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2007-01-31
Release date:2007-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.
Nature, 448, 2007
2OQ7
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THE CRYSTAL STRUCTURE OF JMJD2A COMPLEXED WITH NI AND N-OXALYLGLYCINE
Descriptor:JmjC domain-containing histone demethylation protein 3A, NICKEL (II) ION, ZINC ION, ...
Authors:Kavanagh, K.L., Ng, S.S., Pilka, E., McDonough, M.A., Savitsky, P., von Delft, F., Arrowsmith, C.H., Weigelt, J., Edwards, A., Sundstrom, M., Schofield, C.J., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2007-01-31
Release date:2007-03-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.
Nature, 448, 2007
2OS2
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CRYSTAL STRUCTURE OF JMJD2A COMPLEXED WITH HISTONE H3 PEPTIDE TRIMETHYLATED AT LYS36
Descriptor:JmjC domain-containing histone demethylation protein 3A, histone 3 peptide, NICKEL (II) ION, ...
Authors:Kavanagh, K.L., Ng, S.S., Pilka, E., McDonough, M.A., Savitsky, P., von Delft, F., Arrowsmith, C.H., Weigelt, J., Edwards, A., Sundstrom, M., Schofield, C.J., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2007-02-05
Release date:2007-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.
Nature, 448, 2007
2OT7
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CRYSTAL STRUCTURE OF JMJD2A COMPLEXED WITH HISTONE H3 PEPTIDE MONOMETHYLATED AT LYS9
Descriptor:JmjC domain-containing histone demethylation protein 3A, histone 3 K9 monomethyl, NICKEL (II) ION, ...
Authors:Kavanagh, K.L., Ng, S.S., Pilka, E., McDonough, M.A., Savitsky, P., von Delft, F., Arrowsmith, C.H., Weigelt, J., Edwards, A., Sundstrom, M., Schofield, C.J., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2007-02-07
Release date:2007-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.135 Å)
Cite:Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.
Nature, 448, 2007
2OX0
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CRYSTAL STRUCTURE OF JMJD2A COMPLEXED WITH HISTONE H3 PEPTIDE DIMETHYLATED AT LYS9
Descriptor:JmjC domain-containing histone demethylation protein 3A, synthetic peptide, NICKEL (II) ION, ...
Authors:Pilka, E.S., Ng, S.S., Kavanagh, K.L., McDonough, M.A., Savitsky, P., von Delft, F., Arrowsmith, C.H., Weigelt, J., Edwards, A., Sundstrom, M., Schofield, C.J., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2007-02-19
Release date:2007-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.
Nature, 448, 2007
2P5B
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THE COMPLEX STRUCTURE OF JMJD2A AND TRIMETHYLATED H3K36 PEPTIDE
Descriptor:JmjC domain-containing histone demethylation protein 3A, Histone H3, ZINC ION, ...
Authors:Zhang, G., Chen, Z., Zang, J., Hong, X., Shi, Y.
Deposit date:2007-03-14
Release date:2007-06-12
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural basis of the recognition of a methylated histone tail by JMJD2A.
Proc.Natl.Acad.Sci.USA, 104, 2007
2PXJ
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THE COMPLEX STRUCTURE OF JMJD2A AND MONOMETHYLATED H3K36 PEPTIDE
Descriptor:JmjC domain-containing histone demethylation protein 3A, monomethylated Histone H3K36 peptide, ZINC ION, ...
Authors:Chen, Z., Zang, J., Kappler, J., Hong, X., Crawford, F., Zhang, G.
Deposit date:2007-05-14
Release date:2007-06-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of the recognition of a methylated histone tail by JMJD2A
Proc.Natl.Acad.Sci.Usa, 104, 2007
2Q8C
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CRYSTAL STRUCTURE OF JMJD2A IN TERNARY COMPLEX WITH AN HISTONE H3K9ME3 PEPTIDE AND 2-OXOGLUTARATE
Descriptor:JmjC domain-containing histone demethylation protein 3A, HISTONE 3 PEPTIDE, NICKEL (II) ION, ...
Authors:Couture, J.-F., Collazo, E., Ortiz-Tello, P., Brunzelle, J.S., Trievel, R.C.
Deposit date:2007-06-10
Release date:2007-07-03
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.047 Å)
Cite:Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase.
Nat.Struct.Mol.Biol., 14, 2007
2Q8D
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CRYSTAL STRUCTURE OF JMJ2D2A IN TERNARY COMPLEX WITH HISTONE H3-K36ME2 AND SUCCINATE
Descriptor:JmjC domain-containing histone demethylation protein 3A, HISTONE 3 peptide, NICKEL (II) ION, ...
Authors:Couture, J.-F., Collazo, E., Ortiz-Tello, P., Brunzelle, J.S., Trievel, R.C.
Deposit date:2007-06-10
Release date:2007-07-03
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase.
Nat.Struct.Mol.Biol., 14, 2007
2Q8E
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SPECIFICITY AND MECHANISM OF JMJD2A, A TRIMETHYLLYSINE-SPECIFIC HISTONE DEMETHYLASE
Descriptor:JmjC domain-containing histone demethylation protein 3A, histone 3 peptide, NICKEL (II) ION, ...
Authors:Couture, J.-F., Collazo, E., Ortiz-Tello, P., Brunzelle, J.S., Trievel, R.C.
Deposit date:2007-06-10
Release date:2007-07-03
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase.
Nat.Struct.Mol.Biol., 14, 2007
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