PDB: 87 resultsInfo pagesStatus searchChemie searchBIRD

---

7XIN	Crystal structure of DODC from Pseudomonas Descriptor: DOPA decarboxylase, PYRIDOXAL-5'-PHOSPHATE Authors: Li, X, Zhou, Y.L, Liao, L.J, Liu, X.K, Liu, B, Guo, Y, Feng, Z, Sun, D.Y, Zeng, Z.X. Deposit date: 2022-04-13 Release date: 2023-04-19 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of DODC from Pseudomonas To Be Published
3MAD	Crystal structure of StSPL (symmetric form) Descriptor: PHOSPHATE ION, Sphingosine-1-phosphate lyase Authors: Bourquin, F, Grutter, M.G, Capitani, G. Deposit date: 2010-03-23 Release date: 2010-08-18 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism. Structure, 18, 2010
1PMM	Crystal structure of Escherichia coli GadB (low pH) Descriptor: ACETIC ACID, Glutamate decarboxylase beta, PYRIDOXAL-5'-PHOSPHATE Authors: Capitani, G, De Biase, D, Aurizi, C, Gut, H, Bossa, F, Grutter, M.G. Deposit date: 2003-06-11 Release date: 2004-02-17 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure and functional analysis of escherichia coli glutamate decarboxylase Embo J., 22, 2003
1XEY	Crystal structure of the complex of Escherichia coli GADA with glutarate at 2.05 A resolution Descriptor: ACETATE ION, GLUTARIC ACID, Glutamate decarboxylase alpha, ... Authors: Dutyshev, D.I, Darii, E.L, Fomenkova, N.P, Pechik, I.V, Polyakov, K.M, Nikonov, S.V, Andreeva, N.S, Sukhareva, B.S. Deposit date: 2004-09-13 Release date: 2004-10-05 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structure of Escherichia coli glutamate decarboxylase (GADalpha) in complex with glutarate at 2.05 angstroms resolution. Acta Crystallogr.,Sect.D, 61, 2005
6EEW	Crystal structure of Catharanthus roseus tryptophan decarboxylase in complex with L-tryptophan Descriptor: Aromatic-L-amino-acid decarboxylase, CALCIUM ION, TRYPTOPHAN Authors: Torrens-Spence, M.P, Chiang, Y, Smith, T, Vicent, M.A, Wang, Y, Weng, J.K. Deposit date: 2018-08-15 Release date: 2018-09-19 Last modified: 2020-06-03 Method: X-RAY DIFFRACTION (2.05002069 Å) Cite: Structural basis for divergent and convergent evolution of catalytic machineries in plant aromatic amino acid decarboxylase proteins. Proc.Natl.Acad.Sci.USA, 117, 2020
3MBB	Crystal structure of StSPL - apo form, after treatment with semicarbazide Descriptor: 1,2-ETHANEDIOL, PHOSPHATE ION, Putative sphingosine-1-phosphate lyase, ... Authors: Bourquin, F, Grutter, M.G, Capitani, G. Deposit date: 2010-03-25 Release date: 2010-08-18 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.051 Å) Cite: Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism. Structure, 18, 2010
7EIW	Human histidine decarboxylase mutant Y334F reacted with histidine Descriptor: Histidine decarboxylase, PYRIDOXAL-5'-PHOSPHATE Authors: Komori, H. Deposit date: 2021-04-01 Release date: 2022-04-06 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural analysis of the HDC Y334F mutant J Biol Macromol, 21, 2021
6ZEK	Crystal structure of mouse CSAD Descriptor: CHLORIDE ION, COBALT (II) ION, Cysteine sulfinic acid decarboxylase, ... Authors: Mahootchi, E, Raasakka, A, Haavik, J, Kursula, P. Deposit date: 2020-06-16 Release date: 2021-04-28 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure and substrate specificity determinants of the taurine biosynthetic enzyme cysteine sulphinic acid decarboxylase. J.Struct.Biol., 213, 2021
5O5C	The crystal structure of DfoJ, the desferrioxamine biosynthetic pathway lysine decarboxylase from the fire blight disease pathogen Erwinia amylovora Descriptor: PYRIDOXAL-5'-PHOSPHATE, Putative decarboxylase involved in desferrioxamine biosynthesis Authors: Salomone-Stagni, M, Bartho, J.D, Polsinelli, I, Bellini, D, Walsh, M.A, Demitri, N, Benini, S. Deposit date: 2017-06-01 Release date: 2018-02-28 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.1 Å) Cite: A complete structural characterization of the desferrioxamine E biosynthetic pathway from the fire blight pathogen Erwinia amylovora. J. Struct. Biol., 202, 2018
3VP6	Structural characterization of Glutamic Acid Decarboxylase; insights into the mechanism of autoinactivation Descriptor: 4-oxo-4H-pyran-2,6-dicarboxylic acid, GLYCEROL, Glutamate decarboxylase 1 Authors: Langendorf, C.G, Tuck, K.L, Key, T.L.G, Rosado, C.J, Wong, A.S.M, Fenalti, G, Buckle, A.M, Law, R.H.P, Whisstock, J.C. Deposit date: 2012-02-27 Release date: 2013-01-16 Last modified: 2013-08-14 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural characterization of the mechanism through which human glutamic acid decarboxylase auto-activates Biosci.Rep., 33, 2013
6M4Y	Structure of a R371A mutant of a Group II PLP dependent decarboxylase from Methanocaldococcus jannaschii Descriptor: GLYCEROL, L-tyrosine/L-aspartate decarboxylase, SULFATE ION Authors: Manoj, N, Chellam Gayathri, S. Deposit date: 2020-03-09 Release date: 2020-12-02 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystallographic Snapshots of the Dunathan and Quinonoid Intermediates provide Insights into the Reaction Mechanism of Group II Decarboxylases. J.Mol.Biol., 432, 2020
5K1R	Structure of Burkholderia pseudomallei K96243 sphingosine-1-phosphate lyase Bpss2021 Descriptor: Burkholderia pseudomallei sphingosine-1-phosphate lyase Bpss2021, PYRIDOXAL-5'-PHOSPHATE Authors: Mclean, C.J, Campopiano, D.J, Marles-Wright, J. Deposit date: 2016-05-18 Release date: 2016-11-02 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.104 Å) Cite: Characterization of homologous sphingosine-1-phosphate lyase isoforms in the bacterial pathogen Burkholderia pseudomallei. J. Lipid Res., 58, 2017
3F9T	Crystal structure of L-tyrosine decarboxylase MfnA (EC 4.1.1.25) (NP_247014.1) from METHANOCOCCUS JANNASCHII at 2.11 A resolution Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, L-tyrosine decarboxylase MfnA, PYRIDOXAL-5'-PHOSPHATE Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2008-11-14 Release date: 2008-11-25 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (2.11 Å) Cite: Crystal structure of L-tyrosine decarboxylase MfnA (EC 4.1.1.25) (NP_247014.1) from METHANOCOCCUS JANNASCHII at 2.11 A resolution To be published
7CWX	Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis Descriptor: DI(HYDROXYETHYL)ETHER, Decarboxylase, GLYCEROL Authors: Yu, X, Gong, M, Huang, J, Liu, W, Chen, C, Guo, R. Deposit date: 2020-09-01 Release date: 2021-09-01 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis to be published
5GP4	Lactobacillus brevis CGMCC 1306 Glutamate decarboxylase Descriptor: Glutamate decarboxylase, PYRIDOXAL-5'-PHOSPHATE Authors: Mei, L, Huang, J. Deposit date: 2016-07-31 Release date: 2017-08-02 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.16 Å) Cite: Lactobacillus brevis CGMCC 1306 glutamate decarboxylase: Crystal structure and functional analysis. Biochem. Biophys. Res. Commun., 503, 2018
7EIY	Human histidine decarboxylase mutant Y334F soaking with histidine Descriptor: HISTIDINE, Histidine decarboxylase, PYRIDOXAL-5'-PHOSPHATE, ... Authors: Komori, H. Deposit date: 2021-04-01 Release date: 2022-04-06 Last modified: 2023-04-19 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural analysis of the HDC Y334F mutant J Biol Macromol, 21, 2021
6JRL	Crystal structure of Drosophila alpha methyldopa-resistant protein/3,4-dihydroxyphenylacetaldehyde synthase Descriptor: 3,4-dihydroxyphenylacetaldehyde synthase Authors: Wei, S, Vavrick, C.J, Guan, H, Liao, C, Robinson, H, Liang, J, Wang, D, Han, Q, Li, J. Deposit date: 2019-04-04 Release date: 2019-04-17 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural basis for the bifunctional mechanism of Drosophila alpha methyldopa-resistant protein/3,4-dihydroxyphenylacetaldehyde synthase To Be Published
4RIZ	The crystal structure of Y333Q mutant pyridoxal-dependent decarboxylase from Sphaerobacter thermophilus dsm 20745 Descriptor: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, GLYCEROL, Pyridoxal-dependent decarboxylase, ... Authors: Wu, R, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) Deposit date: 2014-10-07 Release date: 2014-11-12 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.2 Å) Cite: The crystal structure of y333q mutant pyridoxal-dependent decarboxylase from sphaerobacter thermophilus dsm 20745 To be Published
5EUD	S1P Lyase Bacterial Surrogate bound to N-(1-(4-(3-hydroxyprop-1-yn-1-yl)phenyl)-2-((4-methoxy-2,5-dimethylbenzyl)amino)ethyl)-5-methylisoxazole-3-carboxamide Descriptor: PHOSPHATE ION, Putative sphingosine-1-phosphate lyase, ~{N}-[(1~{S})-2-[(4-methoxy-2,5-dimethyl-phenyl)methylamino]-1-[4-(3-oxidanylprop-1-ynyl)phenyl]ethyl]-5-methyl-1,2-oxazole-3-carboxamide Authors: Argiriadi, M.A, Banach, D, Radziejewska, E, Marchie, S, DiMauro, J, Dinges, J, Dominguez, E, Hutchins, C, Judge, R.A, Queeney, K, Wallace, G, Harris, C.M. Deposit date: 2015-11-18 Release date: 2016-03-16 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.24 Å) Cite: Creation of a S1P Lyase bacterial surrogate for structure-based drug design. Bioorg.Med.Chem.Lett., 26, 2016
1JS3	Crystal structure of dopa decarboxylase in complex with the inhibitor carbidopa Descriptor: CARBIDOPA, DOPA decarboxylase, PYRIDOXAL-5'-PHOSPHATE, ... Authors: Burkhard, P, Dominici, P, Borri-Voltattorni, C, Jansonius, J.N, Malashkevich, V.N. Deposit date: 2001-08-16 Release date: 2001-10-26 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structural insight into Parkinson's disease treatment from drug-inhibited DOPA decarboxylase. Nat.Struct.Biol., 8, 2001
6KHN	Crystal structure of Oryza sativa TDC with PLP and SEROTONIN Descriptor: ACETATE ION, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... Authors: Zhou, Y.Z, Liao, L.J, Liu, X.K, Guo, Y, Zhao, Y.C, Zeng, Z.X. Deposit date: 2019-07-16 Release date: 2020-07-15 Method: X-RAY DIFFRACTION (2.293 Å) Cite: Crystal structure ofOryza sativaTDC reveals the substrate specificity for TDC-mediated melatonin biosynthesis. J Adv Res, 24, 2020
6KHP	Crystal structure of Oryza sativa TDC with PLP and tryptamine Descriptor: 2-(1H-INDOL-3-YL)ETHANAMINE, ACETATE ION, CALCIUM ION, ... Authors: Zhou, Y.Z, Liao, L.J, Liu, X.K, Guo, Y, Zhao, Y.C, Zeng, Z.X. Deposit date: 2019-07-16 Release date: 2020-07-15 Method: X-RAY DIFFRACTION (2.299 Å) Cite: Crystal structure ofOryza sativaTDC reveals the substrate specificity for TDC-mediated melatonin biosynthesis. J Adv Res, 24, 2020
2OKK	The X-ray crystal structure of the 65kDa isoform of Glutamic Acid Decarboxylase (GAD65) Descriptor: GAMMA-AMINO-BUTANOIC ACID, GLYCEROL, Glutamate decarboxylase 2 Authors: Buckle, A.M, Fenalti, G, Law, R.H.P, Whisstock, J.C. Deposit date: 2007-01-17 Release date: 2007-03-27 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.3 Å) Cite: GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop. Nat.Struct.Mol.Biol., 14, 2007
2OKJ	The X-ray crystal structure of the 67kDa isoform of Glutamic Acid Decarboxylase (GAD67) Descriptor: 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]BUTANOIC ACID, GAMMA-AMINO-BUTANOIC ACID, Glutamate decarboxylase 1 Authors: Buckle, A.M, Fenalti, G, Law, R.H.P, Whisstock, J.C. Deposit date: 2007-01-17 Release date: 2007-03-27 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.3 Å) Cite: GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop. Nat.Struct.Mol.Biol., 14, 2007
1PMO	Crystal structure of Escherichia coli GadB (neutral pH) Descriptor: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glutamate decarboxylase beta Authors: Capitani, G, De Biase, D, Aurizi, C, Gut, H, Bossa, F, Grutter, M.G. Deposit date: 2003-06-11 Release date: 2004-02-17 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure and functional analysis of escherichia coli glutamate decarboxylase Embo J., 22, 2003

<1234>