6M4Y

Structure of a R371A mutant of a Group II PLP dependent decarboxylase from Methanocaldococcus jannaschii

Summary for 6M4Y

Entry DOI	10.2210/pdb6m4y/pdb
Related	6JY1 6LDR 6LDS 6LDT
Descriptor	L-tyrosine/L-aspartate decarboxylase, SULFATE ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	plp dependent decarboxylase, catalytic mutant, protein conformation, llp, internal aldimine, tyrosine, tyrosine decarboxylase, structure-activity relationship, lyase
Biological source	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Total number of polymer chains	1
Total formula weight	48141.15
Authors	Manoj, N.,Chellam Gayathri, S. (deposition date: 2020-03-09, release date: 2020-12-02, Last modification date: 2023-11-29)
Primary citation	Gayathri, S.C.,Manoj, N. Crystallographic Snapshots of the Dunathan and Quinonoid Intermediates provide Insights into the Reaction Mechanism of Group II Decarboxylases. J.Mol.Biol., 432:166692-166692, 2020 Cited by PubMed: 33122004 DOI: 10.1016/j.jmb.2020.10.026 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation