6LDT

K245A mutant of L-tyrosine decarboxylase from Methanocaldococcus jannaschii complexed with a post-decarboxylation quinonoid-like intermediate formed with L-tyrosine

Summary for 6LDT

Entry DOI	10.2210/pdb6ldt/pdb
Related	6JY1 6LDR 6LDS
Descriptor	L-tyrosine/L-aspartate decarboxylase, GLYCEROL, SULFATE ION, ... (5 entities in total)
Functional Keywords	plp dependent decarboxylase, catalytic domain, models, molecular, protein conformation, plp, tyrosine, quinonoid, tyrosine decarboxylase, structure-activity relationship, dunathan alignment, lyase
Biological source	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Total number of polymer chains	1
Total formula weight	48339.38
Authors	Manoj, N.,Chellam Gayathri, S. (deposition date: 2019-11-23, release date: 2020-12-02, Last modification date: 2023-11-22)
Primary citation	Chellam Gayathri, S.,Manoj, N. Structural insights into the mechanism of internal aldimine formation and catalytic loop dynamics in an archaeal Group II decarboxylase. J.Struct.Biol., 208:137-151, 2019 Cited by PubMed: 31445086 DOI: 10.1016/j.jsb.2019.08.009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.93 Å)

Structure validation