3VP6
Structural characterization of Glutamic Acid Decarboxylase; insights into the mechanism of autoinactivation
Summary for 3VP6
Entry DOI | 10.2210/pdb3vp6/pdb |
Descriptor | Glutamate decarboxylase 1, 4-oxo-4H-pyran-2,6-dicarboxylic acid, GLYCEROL, ... (4 entities in total) |
Functional Keywords | catalytic loop swap, lyase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 117411.82 |
Authors | Langendorf, C.G.,Tuck, K.L.,Key, T.L.G.,Rosado, C.J.,Wong, A.S.M.,Fenalti, G.,Buckle, A.M.,Law, R.H.P.,Whisstock, J.C. (deposition date: 2012-02-27, release date: 2013-01-16, Last modification date: 2013-08-14) |
Primary citation | Langendorf, C.G.,Tuck, K.L.,Key, T.L.G.,Fenalti, G.,Pike, R.N.,Rosado, C.J.,Wong, A.S.M.,Buckle, A.M.,Law, R.H.P.,Whisstock, J.C. Structural characterization of the mechanism through which human glutamic acid decarboxylase auto-activates Biosci.Rep., 33:137-144, 2013 Cited by PubMed: 23126365DOI: 10.1042/BSR20120111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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