1JS3

Crystal structure of dopa decarboxylase in complex with the inhibitor carbidopa

Summary for 1JS3

• Entry DOI: 10.2210/pdb1js3/pdb
• Related: 1JS6
• Descriptor: DOPA decarboxylase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE, ... (5 entities in total)
• Functional Keywords: dopa decarboxylase, carbidopa, parkinson's disease, vitamin b6, lyase
• Biological source: Sus scrofa (pig)
• Total number of polymer chains: 2
• Total formula weight: 109335.34

Authors

Burkhard, P.,Dominici, P.,Borri-Voltattorni, C.,Jansonius, J.N.,Malashkevich, V.N. (deposition date: 2001-08-16, release date: 2001-10-26, Last modification date: 2024-02-07)

• Primary citation: Burkhard, P.,Dominici, P.,Borri-Voltattorni, C.,Jansonius, J.N.,Malashkevich, V.N.; Structural insight into Parkinson's disease treatment from drug-inhibited DOPA decarboxylase.; Nat.Struct.Biol., 8:963-967, 2001; PubMed: 11685243; DOI: 10.1038/nsb1101-963

Experimental method

X-RAY DIFFRACTION (2.25 Å)