PDB: 56 件ウェブページステータス検索Chemie searchBIRD

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6NIF	crystal structure of human REV7-RAN complex 分子名称: hREV7, GTP-binding nuclear protein Ran, hREV3 fusion 著者 Wang, X, Pertz, L, Hua, D.P, Zhang, T.Q, Listovsky, T, Xie, W. 登録日 2018-12-27 公開日 2019-09-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.002 Å) 主引用文献 REV7 has a dynamic adaptor region to accommodate small GTPase RAN/ShigellaIpaB ligands, and its activity is regulated by the RanGTP/GDP switch. J.Biol.Chem., 294, 2019
5O8K	Crystal structure of mammalian Rev7 in complex with Rev3 1875-1895 分子名称: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B 著者 Emamzadah, S, Tropia, L, Huber, F, Halazonetis, T. 登録日 2017-06-13 公開日 2018-06-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of mammalian Rev7 in complex with Rev3 1875-1895 To Be Published
8J69	Crystal structure of HORMA domain-containing protein 1 (HORMAD1) from Homo sapiens 分子名称: HORMA domain-containing protein 1 著者 Yang, X.Y, Liu, X.H. 登録日 2023-04-25 公開日 2023-09-20 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Structural and biochemical insights into the interaction mechanism underlying HORMAD1 and its partner proteins. Structure, 31, 2023
3GMH	Crystal Structure of the Mad2 Dimer 分子名称: Mitotic spindle assembly checkpoint protein MAD2A, SULFATE ION 著者 Ozkan, E, Luo, X, Machius, M, Yu, H, Deisenhofer, J. 登録日 2009-03-13 公開日 2010-11-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.95 Å) 主引用文献 Structure of an intermediate conformer of the spindle checkpoint protein Mad2. Proc.Natl.Acad.Sci.USA, 112, 2015
8CXK	Structure of the C. elegans HIM-3 R93Y mutant 分子名称: HORMA domain-containing protein 著者 Ego, K.M, Russo, A, Giacopazzi, S, Deshong, A, Menon, M, Ortiz, V, Bhalla, N, Corbett, K.D. 登録日 2022-05-21 公開日 2023-05-17 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 The conserved AAA ATPase PCH-2 distributes its regulation of meiotic prophase events through multiple meiotic HORMADs in C. elegans. Plos Genet., 19, 2023
1KLQ	The Mad2 Spindle Checkpoint Protein Undergoes Similar Major Conformational Changes upon Binding to Either Mad1 or Cdc20 分子名称: MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A, Mad2-binding peptide 著者 Luo, X, Tang, Z, Rizo, J, Yu, H. 登録日 2001-12-12 公開日 2002-01-25 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20. Mol.Cell, 9, 2002
1S2H	The Mad2 spindle checkpoint protein possesses two distinct natively folded states 分子名称: Mitotic spindle assembly checkpoint protein MAD2A 著者 Luo, X, Tang, Z, Xia, G, Wassmann, K, Matsumoto, T, Rizo, J, Yu, H. 登録日 2004-01-08 公開日 2004-03-30 最終更新日 2021-10-27 実験手法 SOLUTION NMR 主引用文献 The Mad2 spindle checkpoint protein has two distinct natively folded states. Nat.Struct.Mol.Biol., 11, 2004
3ABD	Structure of human REV7 in complex with a human REV3 fragment in a monoclinic crystal 分子名称: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B 著者 Hara, K, Hashimoto, H, Murakumo, Y, Kobayashi, S, Kogame, T, Unzai, S, Akashi, S, Takeda, S, Shimizu, T, Sato, M. 登録日 2009-12-07 公開日 2010-02-16 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase {zeta} and REV1 J.Biol.Chem., 285, 2010
3ABE	Structure of human REV7 in complex with a human REV3 fragment in a tetragonal crystal 分子名称: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B 著者 Hara, K, Hashimoto, H, Murakumo, Y, Kobayashi, S, Kogame, T, Unzai, S, Akashi, S, Takeda, S, Shimizu, T, Sato, M. 登録日 2009-12-07 公開日 2010-02-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase {zeta} and REV1 J.Biol.Chem., 285, 2010
2V64	Crystallographic structure of the conformational dimer of the Spindle Assembly Checkpoint protein Mad2. 分子名称: MBP1, MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A 著者 Mapelli, M, Massimiliano, L, Santaguida, S, Musacchio, A. 登録日 2007-07-13 公開日 2007-11-27 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The MAD2 Conformational Dimer: Structure and Implications for the Spindle Assembly Checkpoint Cell(Cambridge,Mass.), 131, 2007
2VFX	Structure of the Symmetric Mad2 Dimer 分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, ... 著者 Yang, M, Li, B, Liu, C.-J, Tomchick, D.R, Machius, M, Rizo, J, Yu, H, Luo, X. 登録日 2007-11-05 公開日 2008-03-18 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Insights Into MAD2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric MAD2 Dimer. Plos Biol., 6, 2008
1DUJ	SOLUTION STRUCTURE OF THE SPINDLE ASSEMBLY CHECKPOINT PROTEIN HUMAN MAD2 分子名称: SPINDLE ASSEMBLY CHECKPOINT PROTEIN 著者 Luo, X, Fang, G, Coldiron, M, Lin, Y, Yu, H. 登録日 2000-01-17 公開日 2000-03-08 最終更新日 2022-12-21 実験手法 SOLUTION NMR 主引用文献 Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20. Nat.Struct.Biol., 7, 2000
1GO4	Crystal structure of Mad1-Mad2 reveals a conserved Mad2 binding motif in Mad1 and Cdc20. 分子名称: Mitotic spindle assembly checkpoint protein MAD1, Mitotic spindle assembly checkpoint protein MAD2A 著者 Sironi, L, Mapelli, M, Jeang, K.T, Musacchio, A. 登録日 2001-10-17 公開日 2002-05-16 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint. EMBO J., 21, 2002
6EKM	Crystal structure of mammalian Rev7 in complex with human Rev3 second binding site 分子名称: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B 著者 Huber, F, Tropia, L, Emamzadah, S, Halazonetis, T. 登録日 2017-09-26 公開日 2018-10-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Crystal structure of mammalian Rev7 in complex with human Rev3 To Be Published
6EKJ	Crystal structure of mammalian Rev7 in complex with human Chromosome alignment-maintaining phosphoprotein 1 分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Chromosome alignment-maintaining phosphoprotein 1, Mitotic spindle assembly checkpoint protein MAD2B 著者 Huber, F, Tropia, L, Emamzadah, S, Halazonetis, T. 登録日 2017-09-26 公開日 2018-10-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of mammalian Rev7 in complex with Champ1 - CAPS molecule To Be Published
6EKL	Crystal structure of mammalian Rev7 in complex with human Chromosome alignment-maintaining phosphoprotein 1 分子名称: Chromosome alignment-maintaining phosphoprotein 1, Mitotic spindle assembly checkpoint protein MAD2B 著者 Huber, F, Tropia, L, Emamzadah, S, Halazonetis, T. 登録日 2017-09-26 公開日 2018-10-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of mammalian Rev7 in complex with Champ1 To Be Published
5XPT	Crystal structure of MAD2L2/REV7 in complex with a CAMP fragment in a tetragonal crystal 分子名称: Chromosome alignment-maintaining phosphoprotein 1, Mitotic spindle assembly checkpoint protein MAD2B 著者 Hara, K, Taharazako, S, Hashimoto, H. 登録日 2017-06-05 公開日 2017-09-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.102 Å) 主引用文献 Dynamic feature of mitotic arrest deficient 2-like protein 2 (MAD2L2) and structural basis for its interaction with chromosome alignment-maintaining phosphoprotein (CAMP). J. Biol. Chem., 292, 2017
5XPU	Crystal structure of MAD2L2/REV7 in complex with a CAMP fragment in a monoclinic crystal 分子名称: Chromosome alignment-maintaining phosphoprotein 1, Mitotic spindle assembly checkpoint protein MAD2B 著者 Hara, K, Taharazako, S, Hashimoto, H. 登録日 2017-06-05 公開日 2017-09-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.304 Å) 主引用文献 Dynamic feature of mitotic arrest deficient 2-like protein 2 (MAD2L2) and structural basis for its interaction with chromosome alignment-maintaining phosphoprotein (CAMP). J. Biol. Chem., 292, 2017
6BCD	Crystal structure of Rev7-K44A/R124A/A135D in complex with Rev3-RBM2 (residues 1988-2014) 分子名称: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B 著者 Rizzo, A.A, Hao, B, Li, Y, Korzhnev, D.M. 登録日 2017-10-20 公開日 2018-08-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BC8	Crystal structure of Rev7-R124A/Rev3-RBM2 (residues 1988-2014) complex 分子名称: ACETATE ION, DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B, ... 著者 Rizzo, A.A, Hao, B, Li, Y, Korzhnev, D.M. 登録日 2017-10-20 公開日 2018-08-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BI7	Crystal structure of Rev7-WT/Rev3 as a monomer under high-salt conditions 分子名称: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B 著者 Rizzo, A.A, Korzhnev, D.M, Hao, B, Li, Y. 登録日 2017-11-01 公開日 2018-08-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6K08	Crystal structure of REV7(R124A/A135D) in complex with a Shieldin3 fragment 分子名称: Mitotic spindle assembly checkpoint protein MAD2B, SULFATE ION, Shieldin complex subunit 3 著者 Zhang, F, Dai, Y. 登録日 2019-05-05 公開日 2019-12-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.312 Å) 主引用文献 Structural basis for shieldin complex subunit 3-mediated recruitment of the checkpoint protein REV7 during DNA double-strand break repair. J.Biol.Chem., 295, 2020
6K07	Crystal structure of REV7(R124A) in complex with a Shieldin3 fragment 分子名称: Mitotic spindle assembly checkpoint protein MAD2B, SULFATE ION, Shieldin complex subunit 3 著者 Zhang, F, Dai, Y. 登録日 2019-05-05 公開日 2019-12-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Structural basis for shieldin complex subunit 3-mediated recruitment of the checkpoint protein REV7 during DNA double-strand break repair. J.Biol.Chem., 295, 2020
6KTO	Crystal structure of human SHLD3-C-REV7-O-REV7-SHLD2 complex 分子名称: Mitotic spindle assembly checkpoint protein MAD2B, Shieldin complex subunit 2, Shieldin complex subunit 3 著者 Liang, L, Yin, Y. 登録日 2019-08-28 公開日 2020-04-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.4497633 Å) 主引用文献 Molecular basis for assembly of the shieldin complex and its implications for NHEJ. Nat Commun, 11, 2020
6M7A	Structure of REV7-R124A complexed with SHLD3(28-73) 分子名称: Mitotic spindle assembly checkpoint protein MAD2B, Shieldin complex subunit 3 著者 Ma, Y.Z, Li, Y, Wu, B.X, Huang, H.D. 登録日 2020-03-18 公開日 2021-01-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of REV7-R124A complexed with SHLD3(28-73) To Be Published

 

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