5XPU

Crystal structure of MAD2L2/REV7 in complex with a CAMP fragment in a monoclinic crystal

Summary for 5XPU

Entry DOI	10.2210/pdb5xpu/pdb
Descriptor	Mitotic spindle assembly checkpoint protein MAD2B, Chromosome alignment-maintaining phosphoprotein 1 (3 entities in total)
Functional Keywords	mad2l2, mad2b, rev7, camp, champ1, transcription-metal binding protein complex, transcription/metal binding protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	28186.58
Authors	Hara, K.,Taharazako, S.,Hashimoto, H. (deposition date: 2017-06-05, release date: 2017-09-20, Last modification date: 2023-11-22)
Primary citation	Hara, K.,Taharazako, S.,Ikeda, M.,Fujita, H.,Mikami, Y.,Kikuchi, S.,Hishiki, A.,Yokoyama, H.,Ishikawa, Y.,Kanno, S.I.,Tanaka, K.,Hashimoto, H. Dynamic feature of mitotic arrest deficient 2-like protein 2 (MAD2L2) and structural basis for its interaction with chromosome alignment-maintaining phosphoprotein (CAMP). J. Biol. Chem., 292:17658-17667, 2017 Cited by PubMed: 28887307 DOI: 10.1074/jbc.M117.804237 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.304 Å)

Structure validation