5XPU

Crystal structure of MAD2L2/REV7 in complex with a CAMP fragment in a monoclinic crystal

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Mitotic spindle assembly checkpoint protein MAD2B	polymer	227	26101.2	1	UniProt (Q9UI95) Pfam (PF02301) In PDB	Homo sapiens (Human)	Mitotic arrest deficient 2-like protein 2,MAD2-like protein 2,REV7 homolog,hREV7
2	B	Chromosome alignment-maintaining phosphoprotein 1	polymer	21	2085.3	1	UniProt (Q96JM3) In PDB	Homo sapiens (Human)	Zinc finger protein 828
3		water	water		18.0	32	Chemie (HOH)

Sequence modifications

A: 1 - 211 (UniProt: Q9UI95)

PDB	External Database	Details
Met -15	-	expression tag
Gly -14	-	expression tag
Ser -13	-	expression tag
Ser -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
Ser -5	-	expression tag
Gln -4	-	expression tag
Asp -3	-	expression tag
Pro -2	-	expression tag
Asn -1	-	expression tag
Ser 0	-	expression tag
Ala 124	Arg 124	engineered mutation

B: 325 - 344 (UniProt: Q96JM3)

PDB	External Database	Details
Met 324	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	28186.6
All*	Total formula weight	28186.6

*Water molecules are not included.